Results 181 to 190 of about 293,994 (314)

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

From cheek to ureter: initial experience and learning curve of single-port robotic buccal mucosa graft ureteroplasty for complex strictures. [PDF]

J Robot Surg
Qi JC, Yang HX, Wang DB, Tang S, Wang RL, Santodirocco L, Alkassis M, Calvo RS, Xue WY, Wang YX, Crivellaro S.   +10 more
europepmc   +1 more source

SuPRA: Surgical Phase Recognition and Anticipation for Intra-Operative Planning

Intra-operative recognition of surgical phases holds significant potential for enhancing real-time contextual awareness in the operating room. However, we argue that online recognition, while beneficial, primarily lends itself to post-operative video ...
Granados, Alejandro, Dasgupta, Prokar, Boels, Maxence, Liu, Yang, Ourselin, Sebastien   +4 more
core  

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

The Use of Hemostatic Agents to Decrease Surgical Drain Time in General Plastic Surgery Procedures. [PDF]

Plast Reconstr Surg Glob Open
Olano A, Namazian S, Martin A, King CA, Chahine EM, Nardello S.   +5 more
europepmc   +1 more source

Prevalence and patterns of anxiety in patients undergoing gynaecological surgery [PDF]

, 2002
Cox, Christina, Carr, Eloise C.J., Brockbank, Katrina, Allen, Sandra, North, Nigel, Barrett, Richard   +5 more
core  

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

Transition to robotic adrenalectomy: a surgeon-specific learning curve evaluation. [PDF]

J Robot Surg
Akbulut S, Ozel TM, Celik A, Yildiz G, Deniz E, Sari S.   +5 more
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

A prospective randomized study comparing amoxycillin/clavulanate (augmentin) with cefuroxime-metronidazole as prophylaxis in gynaecological surgery. [PDF]

Bioinformation
Soni S, Rathore P, Tiwari A.
europepmc   +1 more source