Results 191 to 200 of about 293,994 (314)

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Functional and Clinical Outcomes after Medial Unicompartmental Knee Arthroplasty Compared with High Tibial Osteotomy in Isolated Medial Compartment Osteoarthritis. [PDF]

J Orthop Case Rep
Kyada M, Khare T, Singh SK, Khan AA, Hegde A, Biswas G.   +5 more
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Robotic single-port (SP) vaginal hysterectomy: the first cases in Europe and surgical steps. [PDF]

Surg Endosc
Otrante L, Moniod L, Rousseau C, Chauleur C.   +3 more
europepmc   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Role of Intraoperative 2D and 3D Fluoroscopy in Identifying Malposition of Screws in Surgical Fixation of Intra-articular Distal Radius Fractures in Comparison to Post-operative Computed Tomography. [PDF]

J Orthop Case Rep
Shah ZA, Nawaz A, Rathod R, Ghoneem M, Ashber I, Ismaily HA.   +5 more
europepmc   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Association between umbilicus-symphysis pubis distance and operative time in transabdominal preperitoneal (TAPP) inguinal hernia repair. [PDF]

Hernia
Gülçek E, Aydoğdu YF, Özaydın S, Büyükkasap Ç.   +3 more
europepmc   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Impact of Resident and Physician Assistant Participation on Cosmetic Plastic Surgery Outcomes in an Appalachia Population. [PDF]

Plast Reconstr Surg Glob Open
Rahimpour A, Yokota Y, Wagner I, Ratliff A, Edah E, Stuart I, Weaver A, Bown P, Barry R.   +8 more
europepmc   +1 more source