Results 201 to 210 of about 1,523,717 (262)

The aldosteronoma resolution score predicts the prognosis of hypertension under two surgical procedures. [PDF]

Front Endocrinol (Lausanne)
Huang Y, Huang Q, Xie Y, Ouyang C, Chen Y, Huang C.   +5 more
europepmc   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Skeletal deformities and surgical procedures in orthognathic surgery patients: a 10-Year retrospective analysis of 1095 cases. [PDF]

BMC Oral Health
Erdem ME, Çoban G, Öztürk T, Yağcı A, Yavuz İ, Irgın C, Gül Amuk N, Türker G, Demirbaş AE, Soylu E, Kaba YN, Bilge S, Asan CY, Topan C, Alkan A.   +14 more
europepmc   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Surgical Procedures for Planting and Revascularization in Catastrophic Hand Injuries and Preliminary Outcome Assessment: Experience of a Regional Care Center. [PDF]

Cureus
González-Vargas IZ, Regil-Juárez C, Salas-Treviño D, González-Cantú CM, Castro-Govea Y.   +4 more
europepmc   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Melatonin and Alprazolam as Anxiolytic Agents in Minor Oral Surgical Procedures - A Comparative Study. [PDF]

Ann Maxillofac Surg
Garikipati SSA, Pratigudupu RS, David JJ, Pandi SC, Badugu VS, Chunduru PS.   +5 more
europepmc   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

orthopedic surgical procedures in patients supported with long-term implantable left ventricular assist devices. [PDF]

Orthop Rev (Pavia)
Qian L, Kukushliev V, Murray J, Odenthal A, Patterson B, Rao A, Harrison A.   +6 more
europepmc   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source