Results 101 to 110 of about 1,872,691 (256)

Clinical review: Goal-directed therapy in high risk surgical patients [PDF]

, 2009
A small group of patients account for the majority of peri-operative morbidity and mortality. These 'high-risk' patients have a poor outcome due to their inability to meet the oxygen transport demands imposed on them by the nature of the surgical ...
Lees, N, Rhodes, A, Hamilton, M
core   +1 more source

Brushing method in the surgical treatment of pilonidal sinus

, 2016
Background/Aim: The aim of study is to assess to examine postoperative complications and recurrences and to aim to determine the efficacy of Povidone-iodine soap brushing (PISB) on surgical treatment of pilonidal sinus.
Kalemoglu, E., Kalemoglu, Murat
core   +1 more source

CYSTOCELE REPAIR BY SYNTHETIC MESH SECURED THROUGH THE OBTURATOR FORAMEN (PERIGEE SYSTEM) [PDF]

, 2008
Cilj rada. Prikazati preliminarne rezultate transobturatornog pristupa korekcije cistocela metodom Perigee. Metode. 22 bolesnice s cistocelom drugog stupnja podvrgnute su u našoj ustanovi metodi Perigee u vremenskom razdoblju između sječnja 2006.
Župić, Tomislav, Lovrić, Helena, Orešković, Slavko, Kalafatić, Držislav, Banović, Maja, Gojević, Ante   +5 more
core   +1 more source

Congenital retrosternal hernias of Morgagni: Manifestation and treatment in children

African Journal of Paediatric Surgery, 2016
Background: Due to scarcity of congenital diaphragmatic hearnias of Morgagni (CDHM), non-specific clinical presentation in the pediatric age group, we aimed to investigate the incidence, clinical manifestations, anatomical characteristics, and develop ...
Oleksii Slepov, Sergii Kurinnyi, Oleksii Ponomarenko, Mikhailo Migur   +3 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Observations from the IMPROVE trial concerning the clinical care of patients with ruptured abdominal aortic aneurysm. [PDF]

, 2013
BACKGROUND: Single-centre series of the management of patients with ruptured abdominal aortic aneurysm (AAA) are usually too small to identify clinical factors that could improve patient outcomes.
Hinchliffe, RJ, Thompson, MM, Bell, R, Greenhalgh, R. M., Ashleigh, R., Grieve, RJ, Ulug, P., Heatley, F., Powell, JT, Sweeting, M. J., Ashleigh, R, Heatley, F, Thompson, S. G., Powell, J. T., Greenhalgh, RM, Gomes, M, Ulug, P, Sweeting, MJ, Gomes, M., ?, ?, Thompson, SG, Hinchliffe, R. J., IMPROVE trial investigators, Thompson, M. M., Bell, Rachel, Grieve, R. J.   +25 more
core   +1 more source

Percutaneous Closure of Postmyocardial Infarction Ventricular Septal Rupture – A Single Center Experience from the Eastern Part of India

Journal of Indian College of Cardiology
Background: Postinfarction ventricular septal rupture (VSR) is a rare but lethal mechanical complication of an acute myocardial infarction (AMI). It results in 90%–95% mortality within 2 months of diagnosis without any kind of intervention.
Nurul Islam, Siddhartha Saha, Ashok Kumar Parida, Satyendra Nath Dutta   +3 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Open surgical repair of abdominal aortic aneurysms and dissecting aneurysms in patients with coronary artery disease: a single-center experience

Zaporožskij Medicinskij Žurnal
Aim. To summarize the experience of pre- and postoperative management of patients with abdominal aortic aneurysms or dissections associated with coronary artery disease (CAD), and to evaluate the effectiveness of open surgical repair combined with ...
I. I. Zhekov, A. V. Rudenko, A. S. Bulakh, I. P. Makohonchuk, K. V. Rudenko   +4 more
doaj   +1 more source