Results 91 to 100 of about 3,958,137 (292)

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Clinical efficacy and safety of different video-assisted thoracoscopic surgery approaches for bullous lung resection: a systematic review and meta-analysis

open access: yesFrontiers in Surgery
ObjectiveThis meta-analysis evaluates the perioperative safety and comparative efficacy of single-port versus multi-port video-assisted thoracoscopic surgery (VATS) for bullous lung resection in patients with primary spontaneous pneumothorax.MethodsA ...
Ting Gao, Xiaopeng He, Peiwen Zhao
doaj   +1 more source

Surgical safety [PDF]

open access: yesThe Annals of The Royal College of Surgeons of England, 2011
J, Smith, A, Edwards
openaire   +2 more sources

Amish buggy safety status report, Ohio Department of Public Safety

open access: yes, 2000
Title from cover of PDF document (viewed Jan. 31, 2006).; "May 2000."; Harvested from the web on 2/6/06This report reflects the results of a yearlong joint project undertaken by the Ohio departments of Public Safety (ODPS) and Transportation (ODOT).

core  

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito   +8 more
wiley   +1 more source

How to Promote Medical Safety on Minimally Invasive Gynecology Surgery – Japan Experience

open access: yesGynecology and Minimally Invasive Therapy
Minimally invasive gynecologic surgery (MIGS) offers significant advantages, but the expansion of its indications and the increasing complexity of cases have introduced new challenges related to surgical safety and standardization.
Osamu Wada-Hiraike
doaj   +1 more source

Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang   +4 more
wiley   +1 more source

Navigating challenges and maximizing potential: Handling complications and constraints in minimally invasive surgery

open access: yesOpen Health
Minimally invasive surgery (MIS) has revolutionized the field of surgery by offering reduced trauma, faster recovery times, and improved patient outcomes compared to traditional open procedures.
Qadrie Zulfkar   +3 more
doaj   +1 more source

Surgical management of intraocular lens dislocation in highly myopic eyes

open access: yesFrontiers in Medicine
ObjectiveTo evaluate the postoperative visual function, intraocular lens (IOL) positional stability and ocular safety of surgical strategies tailored to capsular support status for the treatment of IOL dislocation in patients with high myopia, and to ...
Shiyu Tang   +16 more
doaj   +1 more source

Factors Affecting on the Implementation of Surgical Safety Checklist in Operating Room [PDF]

open access: yesEgyptian Journal of Health Care
Background: The operating room is critical care setting in the hospital and more complications occurs inside it that threaten patient's life. So in 2008 the World Health Organization (WHO) developed the Surgical Safety Checklist (SSC) to improve surgical
Asmaa Elsayed Mostafa Elshereef   +2 more
doaj   +1 more source

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