Results 71 to 80 of about 3,958,137 (292)

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Partial Endothelial Trepanation versus Deep Anterior Lamellar Keratoplasty in keratoconus patients: Results of the PENTACON trial

Journal of Trial and Error
The purpose of this research was to report on the surgical safety and outcomes of two distinct techniques of anterior lamellar corneal surgery: the Big Bubble Deep Anterior Lamellar Keratoplasty (DALK) versus Busin’s Partial ENdothelial Trepanation (PET)
Robert P.L. Wisse, Cathrien A. Eggink, Bart T.H. van Dooren, Allegonda van der Lelij   +3 more
doaj   +1 more source

PROVISION OF SURGICAL SAFETY

Вестник хирургии имени И.И. Грекова, 2017
OBJECTIVE. The research assessed the efficacy of WHO checklist for prevention of avoidable complications in surgery. MATERIALS AND METHODS. The article presents the results of implementation of WHO recommendations (checklist of measures) for prevention ...
V. M. Timerbulatov, Sh. V. Timerbulatov
doaj   +1 more source

Surgical Patient Safety, Thailand Experiences

Siriraj Medical Journal, 2017
No ...
Supakorn Rojananin
doaj   +3 more sources

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

The Impact of Intraoperative CT-Based Navigation in Congenital Craniovertebral Junction Anomalies: New Concepts of Treatment

Brain Sciences
Background: Congenital craniovertebral junction anomalies (CCVJAs) encompass a diverse range of conditions characterized by distorted anatomy and significant variation in the pathways of neurovascular structures.
Giorgio Cracchiolo, Ali Baram, Gabriele Capo, Zefferino Rossini, Marco Riva, Andrea Fanti, Mario De Robertis, Maurizio Fornari, Federico Pessina, Carlo Brembilla   +9 more
doaj   +1 more source

Beta1 subunits enable fentanyl‐induced BK channel activation and opioid regulation of cerebral artery diameter

FEBS Open Bio, EarlyView.
During the current opioid crisis, the majority of overdose deaths are attributed to ultra‐potent synthetic opioids, such as fentanyl. While fentanyl exerts its action via opioid receptors, we propose that potassium channels in the brain blood vessels may also sense fentanyl.
Shiwani Thapa, Mohammed Nooh, Akhil Geddati, Alex Dopico, Anna N. Bukiya   +4 more
wiley   +1 more source

Use of WHO Surgical Safety Checklist among Surgeons in Tamil Nadu and Its Impact in a Surgical Unit

Journal of Pharmacy and Bioallied Sciences
Introduction: Surgery is risky and typically has unnecessary consequences. Globally accepted WHO Surgical Safety Checklists ensure safety standards are followed to reduce these hazards.
Bryan J. D. Dhinahar, Dhinahar Sundararaj, Theogaraj Sundararaj, Cynthia Dhinahar, Joseph Arnold, Ashok K. Shivashankara   +5 more
doaj   +1 more source

Additional file 1: of Utilization of surgical safety checklists by urological surgeons in Germany: a nationwide prospective survey

, 2016
Examples of different surgical safety checklists used to improve patient safety. A: World Health Organization Surgical Safety Checklist, B: Surgical Safety Checklist used in Canada, C: Colorado hospital association Surgical Safety Checklist used in ...
David Schilling (294935), Axel Haferkamp (287281), Hendrik Borgmann (3043635), Michael Reiter (618161), Tanja HĂźsch (3560357), Igor Tsaur (285993), Sarah Helbig (3560351)   +6 more
core   +1 more source