Results 61 to 70 of about 548,621 (295)

A preliminary study of the effect of closed incision management with negative pressure wound therapy over high-risk incisions [PDF]

, 2015
Background Certain postoperative wounds are recognised to be associated with more complications than others and may be termed high-risk. Wound healing can be particularly challenging following high-energy trauma where wound necrosis and infection ...
A Colli, A Koski, A Li, A Wackenfors, A Wackenfors, AE Guille, BJ Stanley, CJ Jordan, D Herscovici Jr, DA Mendonca, David M. R. Sajik, DR Holt, DV Kipaldi, E Krug, EJ Harvey, EJ Timmenga, GI Taylor, GK Berry, GW Stanway, J Bertran, J Compston, J Kanis, JC Murrell, JP Stannard, JP Stannard, JS Weese, JT Thompson, JW Fox, Karen L. Perry, KV Lambert, L Holton, LJ Owen, Lynda Rutherford, M Demaria, M Pachowsky, MF Fay, Mieghan Bruce, MJ Allen, MJ Morykwas, MJ Morywkas, MJ Morywkas, MW Bohling, MW Bohling, N Fitzpatrick, NA Abidi, PC Bristow, PE Banwell, PE Banwell, PM Taylor, R Ben Amotz, R Burkhardt, R Petzina, RP Wilkes, S Karlakki, S Lindstedt, SA Robertson, SP Roch, SZ Chen, TJ Smith, WT DeCarbo   +59 more
core   +3 more sources

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

The Effect of Duration of Disinfection of Bacterial Flora of Surgical Site

نشریه پرستاری ایران, 2008
Background and Aim: Skin disinfection is an effective method of preventing surgical site infection (SSI), but there is controversy about the duration of skin preparation.
Mitra Zandiyeh, Safar Shams Vala, Sayed Reza Borzo, Fatemeh Masome Ghonoti, Saeid Amiri   +4 more
doaj  

Perioperative and anesthetic risk factors of surgical site infection in patients undergoing pancreaticoduodenectomy: A retrospective cohort study.

PLoS ONE, 2020
BackgroundSurgical site infection is a major perioperative issue. The morbidity of surgical site infection is high in major digestive surgery, such as pancreaticoduodenectomy.
Saori Yamamoto, Yusuke Nagamine, Tetsuya Miyashita, Shiono Ito, Yurika Iwasawa, Michihiko Kawai, Shinsaku Saito, Tomohisa Tamai, Takahisa Goto   +8 more
doaj   +1 more source

Human Wounds and Its Burden: An Updated Compendium of Estimates [PDF]

, 2019
Significance: A 2018 retrospective analysis of Medicare beneficiaries identified that ∼8.2 million people had wounds with or without infections. Medicare cost estimates for acute and chronic wound treatments ranged from $28.1 billion to $96.8 billion ...
Sen, Chandan K.
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Topical use of Vancomycin in Craniotomy

Nepal Journal of Neuroscience, 2019
In neurosurgery, surgical site infections are major cause of morbidity and mortality. It has been significant burden in clinical practice, despite of best practices with or without use of antibiotics. Topical antibiotics are one potential method reducing
Bikram Shakya, Bidur KC, Amit Thapa
doaj   +1 more source

Prevention of incisional surgical site infection by subfascial closed suction drainage after open laparotomy: a single surgeon experience in 250 consecutive patients

Patient Safety in Surgery, 2023
Background Open laparotomy with gastroenterological surgery is a surgical procedure results in a relatively high rate (about 10% or more) of incisional surgical site infection (SSI).
Hiroshi Isozaki
doaj   +1 more source

Prognostic factors influencing infectious complications after cytoreductive surgery and HIPEC. Results from a tertiary referral center [PDF]

, 2019
Background. Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) showed promising results in selected patients. High morbidity restrains its wide application.
Carbonari, Ludovica, Cardi, Maurizio, D'Agostino, Claudia, Fonsi, Giovanni Battista, Francesco Di Marzo,, Francesco, Lefoche, LA TORRE, Giuseppe, Sammartino, Paolo, Sibio, Simone   +8 more
core   +1 more source