Results 61 to 70 of about 444,752 (344)

Severe bloodstream infection due to KPC-producer e coli in a renal transplant recipient treated with the double-carbapenem regimen and analysis of in vitro synergy testing a case report [PDF]

, 2016
Transplant recipients are at high risk of infections caused by multidrug resistant microorganisms. Due to the limited thera- peutic options, innovative antimicrobial combinations against carbape- nem-resistant Enterobacteriaceae causing severe infections
CIPOLLA, ALESSIA, D'ABRAMO, ALESSANDRA, DE ANGELIS, Massimiliano, Favaro, Marco, Ferretti, Giancarlo, GIZZI, FRANCESCA, IANNETTA, MARCO, MASCELLINO, Maria Teresa, MASTROIANNI, Claudio Maria, OLIVA, ALESSANDRA, RUSSO, Gianluca, VULLO, Vincenzo   +11 more
core   +1 more source

Surgical Site Infections after Elective Surgery in Pakistan: SURGIPAK Study

Journal of Rawalpindi Medical College, 2015
Background: To determine the incidence of surgical site infections(SSIs), and to document the causative organisms, duration of hospital stay, and therapeutic class of antibiotics administered in surgical prophylaxis in patients undergoing elective ...
Asif Zafar Malik
doaj  

Methods of preventing surgical site infections

Амбулаторная хирургия
Healthcare-associated infections are the most common and relevant to all healthcare facilities of all types. Surgical site infections are the most frequently reported type of healthcare-associated infections.
A. M. Morozov, A. N. Sergeev, V. M. Chervinets, J. V. Chervinets, O. N. Guskova, O. N. Skaryakina, E. N. Egorova   +6 more
doaj   +1 more source

Surgical site Infection after gastrointestinal and hepatobiliary surgeries- A retrospective evaluation from a single center of western India

Journal of Society of Surgeons of Nepal, 2020
Introduction: Aim of our study to evaluate various factors responsible for surgical site infection after gastrointestinal and hepatobiliary surgeries. Methods: Patients who underwent gastrointestinal and hepatobiliary surgery in our department were ...
Bhavin Vasavada, Hardik Patel
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Classification of postoperative surgical site infections from blood measurements with missing data using recurrent neural networks

, 2017
Clinical measurements that can be represented as time series constitute an important fraction of the electronic health records and are often both uncertain and incomplete.
Bianchi, Filippo Maria, Jenssen, Robert, Kampffmeyer, Michael, Mikalsen, Karl Øyvind, Soguero-Ruiz, Cristina, Strauman, Andreas Storvik   +5 more
core   +1 more source

Incidence of surgical site infection following mastectomy with and without immediate reconstruction using private insurer claims data [PDF]

, 2015
OBJECTIVE: The National Healthcare Safety Network classifies breast operations as clean procedures with an expected 1–2% surgical site infection (SSI) incidence.
Ball, Kelly E, Fox, Ida K, Fraser, Victoria J, Margenthaler, Julie A, Mines, Daniel, Nickel, Katelin B, Olsen, Margaret A, Wallace, Anna E   +7 more
core   +2 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Surgical Management of Diabetic Foot Ulcers: A Tanzanian University Teaching Hospital Experience. [PDF]

, 2011
\ud \ud Diabetic foot ulcers (DFUs) pose a therapeutic challenge to surgeons, especially in developing countries where health care resources are limited and the vast majority of patients present to health facilities late with advanced foot ulcers.
Chalya, Phillipo L, Mabula, Joseph B, Dass, Ramesh M, Kabangila, Rodrick, Jaka, Hyasinta, McHembe, Mabula D, Kataraihya, Johannes B, Mbelenge, Nkinda, Gilyoma, Japhet M   +8 more
core   +1 more source