Stage T4B head and neck cancer survival outcome comparisons based on treatment modality: is surgery a viable treatment option? [PDF]
IMPORTANCE: Advanced stage head and neck cancers are often deemed unresectable due to the aggressive nature of the cancer. In evaluating survival patterns of patients with stage IVb tumors, it is valuable to determine whether patients who undergo ...
Kidwai, Neiha
core +1 more source
Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak+14 more
wiley +1 more source
Holmium Laser Enucleation of the Prostate [PDF]
Introduction: Holmium laser enucleation of the prostate (HoLEP) offers superior voiding outcomes to traditional transurethral resection and less morbidity than open simple prostatectomy. Likewise, HoLEP has been determined to result in excellent outcomes
Krambeck, Amy E.+2 more
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This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini+10 more
wiley +1 more source
Spinal Cord Stimulation for Neuropathic Pain: Current Trends and Future Applications
The origin and the neural pathways involved in chronic neuropathic pain are still not extensively understood. For this reason, despite the wide variety of pain medications available on the market, neuropathic pain is challenging to treat.
Ivano Dones, Vincenzo Levi
doaj +1 more source
A case report of Parry Romberg Syndrome initially presenting as periodontitis [PDF]
Parry Romberg Syndrome (PRS) is a rare disorder of progressive hemifacial atrophy, involving soft tissues, fat and occasionally bone. It can co-exist with presentations of Morphea.
Bramley+14 more
core +1 more source
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim+8 more
wiley +1 more source
THE SURGICAL TREATMENT OF TRACHOMA. [PDF]
The scope of the present paper will not admit of a review of all of the operative procedures that have been and are now employed in the treatment of trachoma, even if it were desirable. I shall, therefore, mention but few and, as I believe that a discussion of methods employed by the individual speakers here is more suitable and will be more profitable
openaire +2 more sources
Restorative proctocolectomy with ileal pouch reservoir in ulcerative colitis : the first series from Malta [PDF]
Seventy five to eighty percent of patients with ulcerative colitis are more or less satisfactorily treated medically. Surgery cures the disease, but because proper surgical therapy has until recently necessitated a permanent ileostomy, physicians and ...
Gatt, Dennis
core
Surgical treatment of retrosternal extraosseous Ewing Sarcoma in a 6-years old female: a clamshell approach with hemysternectomy and application of a non-crosslinked extracellular matrix [PDF]
Background Ewing Sarcoma (ES) and Neuroblastoma (NB) belong to a family of tumours of primitive neuroectodermal origin (PNET) that occurs in both bone and soft tissue. Notwithstanding ES and NB are two distinct malignant tumours, sometimes there could be
Angotti, Rossella+9 more
core +3 more sources