Results 161 to 170 of about 15,686,169 (410)

SURGICAL TREATMENT OF GOITER. [PDF]

open access: yesJAMA: The Journal of the American Medical Association, 1906
ABSTRACT PATHOLOGY. For a proper understanding of the subject it is necessary to give a short review of the various pathologic conditions which affect the thyroid gland, together with a brief description of the clinical pictures presented by each.Normally, the thyroid gland, a ductless body, is composed of a vascular stroma supporting acini which are ...
openaire   +2 more sources

Loss of primary cilia promotes EphA2‐mediated endothelial‐to‐mesenchymal transition in the ovarian tumor microenvironment

open access: yesMolecular Oncology, EarlyView.
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho   +11 more
wiley   +1 more source

THE SURGICAL TREATMENT OF GOITER. [PDF]

open access: yesJAMA: The Journal of the American Medical Association, 1904
The statistics of the continental surgeons in reference to goiter have greatly added to the wholesome respect we have held as to their surgical skill. There the various operative methods of affording relief have been advanced to a high state of perfection.
openaire   +2 more sources

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

open access: yesMolecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski   +19 more
wiley   +1 more source

Corrigendum: Yu et al. PPy@Fe3O4 nanoparticles inhibit the proliferation and metastasis of CRC via suppressing the NF-κB signaling pathway and promoting ferroptosis

open access: yesFrontiers in Bioengineering and Biotechnology, 2022
Zhilong Yu   +6 more
doaj   +1 more source

The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological features

open access: yesMolecular Oncology, EarlyView.
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau   +9 more
wiley   +1 more source

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