Results 91 to 100 of about 371,636 (313)

The effect of triclosan coated sutures on rate of Surgical Site Infection after hip and knee replacement : a protocol for a double-blind randomised controlled trial [PDF]

, 2014
Background: 187,000 hip and knee joint replacements are performed every year in the National Health Service (NHS). One of the commonest complications is surgical site infection (SSI), and this represents a significant burden in terms of patient ...
Reed, Mike R., Parsons, Nicholas R., Andrew P Sprowson, Roland Pratt, Asaad, Seif, Kevin Emmerson, Seif Asaad, Scott Muller, Cyrus D Jensen, Nick Parsons, Pratt, Roland, Muller, Scott, Mike R Reed, Ian Carluke, Paul Partington, Jensen, Cyrus D., Partington, Paul, Carluke, Ian, Sprowson, Andrew P., Emmerson, Kevin   +19 more
core   +1 more source

Combined Phase 1/2a Initial Clinical Safety Trials and Proof‐of‐Concept Assessment of a Novel Antimicrobial Peptide KSL‐W Anti‐Plaque Chewing Gum

Clinical and Experimental Dental Research
Objectives The effective control of dental plaque is crucial for oral health, given that pathogenic bacteria in plaque are the primary cause of dental caries.
J. Brett Ryan, Brian J. Kirkwood, Kai P. Leung   +2 more
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

The evidence and the rationale for the use of honey as wound dressing

, 2011
Although there are now several brands and types of honey wound-care products available as registered medical devices, there is little promotional advertising of honey products for wound care. The misconception that there is no evidence to support the use
Molan, Peter C.
core  

Exploring Resilience When Living with a Wound — An Integrative Literature Review [PDF]

, 2014
The psychological impact for patients with wounds can be significant, and adverse psychological effects frequently occur when there are permanent changes in the body’s structure or function.
Karen-leigh Edward, Edward, Karen-Leigh, Karen Ousey, Ousey, Karen   +3 more
core   +1 more source

Combined treatment with chlorhexidine and 0.9% saline in a newborn infant with an infected surgical wound

, 2016
Newborns are more susceptible to infection; this makes proper wound care extremely important in them. Unfortunately, in spite of successful surgery, patients can die as a result of wound area infections.
TEKGÜNDÜZ, Kadir Şerafettin, Yasar Demirelli, KARA, Mustafa, Kadir Serafettin Tekgunduz, Demirelli, Yaşar, Kepenekli, Eda, Caner, İbrahim, Eda Kepenekli, Mustafa Kara   +8 more
core   +2 more sources

Does plastic incise drape prevent recolonization of endogenous skin flora during lumbar spine procedures?

International Journal of Preventive Medicine, 2019
Background: The aim of this study was to compare the PID with bare skin (without PID) regarding bacterial recolonization and bacterial regrowth of the adjacent skin of surgical incision in lumbar spine surgery patients.
Mohammadreza Zarei, Negin Larti, Homayoun Tabesh, Mohammad Ghasembandi, Akram Aarabi   +4 more
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Comparative Study between Surgical Repair of Atrial Septal Defect via Median Sternotomy, Right Submammary Thoracotomy, and Right Vertical Infra-Axillary Thoracotomy

Brazilian Journal of Cardiovascular Surgery
Objective: To compare the results of surgical repair via median sternotomy, right submammary thoracotomy, and right vertical infra-axillary thoracotomy for atrial septal defect (ASD).
Zeng-rong Luo, Qiang Chen, Ling-li Yu, Liang-wan Chen, Zhong-yao Huang   +4 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source