Results 81 to 90 of about 371,636 (313)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Therapie akuter Wunden mit wassergefiltertem Infrarot A (wIRA)

, 2007
Water-filtered infrared-A (wIRA) as a special form of heat radiation with a high tissue penetration and with a low thermal load to the skin surface acts both by thermal and thermic as well as by non-thermal and non-thermic effects.
Mercer, James B., Illing, Peter, Lademann, Jürgen, Lademann, J, Mercer, JB, Hartel, Mark, Hoffmann, Gerd, Hoffmann, G, Hartel, M, Illing, P, Daeschlein, Georg, Daeschlein, G   +11 more
core   +1 more source

Patient involvement in surgical wound care research: A scoping review

, 2020
Active involvement of patients in planning, conducting, and disseminating research has been adopted by many organisations internationally, but the extent to which this occurs in surgical wound care is not evident.
Emma Louise Harbeck, McInnes, Elizabeth Catherine, Carlini, JJ, Gillespie, BM, Pearcy, Josh Michael, Sharon Leanne Latimer, Wendy Pearl Chaboyer, Pearcy, JM, Lin, FF, Latimer, SL, Joan Julie Carlini, Walker, RM, Rachel Michell Walker, Walker, Rachel Michell, Rachel Muir, Chaboyer, WP, Brigid Mary Gillespie, Frances Fengzhi Lin, Chaboyer, Wendy Pearl, Elizabeth Catherine McInnes, Tuffaha, HW, Muir, R, Harbeck, EL, Carlini, Joan Julie, Josh Michael Pearcy, Gillespie, Brigid Mary, Lin, Frances Fengzhi, McInnes, EC, Harbeck, Emma Louise, Tuffaha, Haitham Wadah, Haitham Wadah Tuffaha, Muir, Rachel, Latimer, Sharon Leanne   +32 more
core   +1 more source

Appropriateness and pharmacoeconomics of surgical antimicrobial prophylaxis in open reduction internal fixation surgery practiced in a tertiary hospital compared to recommendations in the national center for disease control guidelines

Perspectives in Clinical Research, 2019
Context: Surgical site infections are frequently observed despite the availability of national guideline on surgical antimicrobial prophylaxis (SAP). These infections increase patient morbidity, mortality, and direct and indirect health-care costs.
Priyanka Kumari, Jayaram B Siddegowda, Vasundara Krishnaiah   +2 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Risk factors for wound infection in surgery for spinal metastasis

, 2015
Wound infection rates are generally higher in patients undergoing surgery for spinal metastasis. Risk factors of wound infection in these patients are poorly understood.
Popta, D., Verma, R. R., Verma, R R, Siddique, Irfan, Stephenson, John, Kumar, Siva, Rodrigues-Pinto, R., Van Popta, Dmitri, van Popta, D, Rodrigues-Pinto, R, Mohammad, S, Mohammad, Saeed, Siddique, I., Siddique, I, Mohammad, S., Verma, Rajat, Rodrigues Pinto, Ricardo, Kumar, S, Stephenson, J, Kumar, S., Stephenson, J.   +20 more
core   +1 more source

Local antituberculosis treatment in nonhealing chronic surgical site tuberculosis: A novel approach to cure nonhealing wound!

Annals of Medical Science and Research
Tuberculosis most commonly affects the lungs and less than 20% of cases showed extrapulmonary involvement. Tuberculosis at the surgical site is described in the medical literature with very few cases of cesarean section at the incision site.
Shital Patil, Deepak Patil, Shubhangi Khule, Gajanan Gondhali   +3 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

The role of honey in the management of wounds

, 1999
The widespread development of antibiotic-resistant bacteria has generated an increasing interest in the use of alternate therapies for the treatment of infected wounds.
Molan, Peter C.
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source