Results 81 to 90 of about 179,458 (296)
Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix
FEBS Letters, EarlyView.The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual +3 more
wiley +1 more source
State and Federal Surplus Program
, 2016 "Revision History: 09/01/2009, Original policy, published as GS-D-06; 09/19/2016, Reformatted and renumbered, updated all sections and subsections, addition of Appendix A-Definitions"--Page 2.; Effective: September 19, 2016.; Harvested from the web on 1 ...
Ohio. General Services Division. State and Federal Surplus Services,
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Engaging Science, Technology, and Society, 2017 This essay offers a perspective on journal impact factor (JIF) centrism in academic evaluation from the vantage point of academic publishing in an increasingly data-driven scholarly environment. The political implications and orientations to the JIF are
Katie Vann
doaj +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Macroeconomic Management: Breaking out of the Debt Trap
Lahore Journal of EconomicsIt is remarkable that from a situation of default and unsustainable fiscal and balance of payments deficit only a few years back, Pakistan has come out of the debt trap, balance of payments turned surplus1, and fiscal deficit has declined below 4 ...
A. R. Kemal
doaj
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Grief, hope and holding surplus house
This contribution to the panel “Taking stock: Design and STS sensibilities” activates socio-materialities that are haunting our contemporary and future livelihoods.
Jönsson, Li +2 more
core +2 more sources
[News Clip: Surplus Foxhole Freddie]
, 1960 Video footage from the WBAP-TV television station in Fort Worth, Texas, to accompany a news story about Foxhole Fred's army surplus store in ...
WBAP-TV (Television station : Fort Worth, Tex.)
core
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source