Results 201 to 210 of about 145,000 (257)

Association Between Neurofilament Light Chain and Real‐World Ambulatory Function in Progressive MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurofilament light chain (NfL) is a biomarker of neuroaxonal injury in multiple sclerosis (MS), yet associations with functional outcomes remain unclear. Longitudinal associations between serum NfL (sNfL) and daily step count (STEPS) from wearable devices were assessed in a large international progressive MS cohort.
Gabby B. Joseph, Megan McCune, Riley Bove, Ahmed Abdelhak, Bruce A. C. Cree, Valerie J. Block   +5 more
wiley   +1 more source

Retraction: TGF-β signaling proteins and CYP24A1 may serve as surrogate markers for progesterone calcitriol treatment in ovarian and endometrial cancers of different histological types. [PDF]

Transl Cancer Res
Editorial Office.
europepmc   +1 more source

Early Clinical and Cerebrospinal Fluid Predictors of 1‐Year Recurrence in Autoimmune GFAP Astrocytopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune glial fibrillary acidic protein astrocytopathy (GFAP‐A) is an inflammatory central nervous system disorder with variable outcomes. Relapse occurs in a subset of patients, but early predictors remain unclear. We aimed to identify admission‐available features associated with 1‐year recurrence and develop an interpretable ...
Qingting Hong, Yuping Xiao, Yuhan Wu, Ziyuan Huang, Weishan Liang, Li Xiao, Yaqing Shu, Tingting Lu, Yanyu Chang, Wei Qiu, Yuge Wang   +10 more
wiley   +1 more source

Flexible evaluation of surrogate markers with Bayesian model averaging. [PDF]

Stat Med
Duan Y, Parast L.
europepmc   +1 more source

Predicting the presence and severity of coronary artery disease using surrogate markers of insulin resistance: A cross-sectional study. [PDF]

ARYA Atheroscler
Jahangiri S, Mosalamiaghili SA, Heydarzadeh R, Yousefzadeh M, Golchin Vafa R, Zarifkar H, Assadian K, Sohrabizadeh S, Zarifkar H, Sadeghi M, Hosseini N, Montaseri M, Hosseini SA, Kojuri J.   +13 more
europepmc   +1 more source

Non-invasive surrogate markers of pulmonary hypertension are associated with poor survival in patients with cancer. [PDF]

BMJ Open Respir Res
Cekay M, Arndt PF, Franken JK, Wilhelm J, Pullamsetti SS, Roller FC, Sommer N, Askevold I, Lüdecke G, Langer C, Stein M, Zeppernick F, Tello K, Sibelius U, Grimminger F, Seeger W, Savai R, Eul B.   +17 more
europepmc   +1 more source

Associations Between Surrogate Markers and Clinical Outcomes for Nononcologic Chronic Disease Treatments.

JAMA
Wallach JD, Yoon S, Doernberg H, Glick LR, Ciani O, Taylor RS, Mooghali M, Ramachandran R, Ross JS.   +8 more
europepmc   +1 more source

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Surrogate markers of rejection

Current Opinion in Organ Transplantation, 2010
There is continued interest in defining viable noninvasive alternatives to endomyocardial biopsy (EMB) for monitoring recipients of orthotopic heart transplantation for episodes of rejection. This review summarizes the evidence of clinical utility for both available and emerging surrogate markers of rejection.A variety of imaging modalities and ...
Bethany A, Austin, David O, Taylor
openaire   +2 more sources

Testing for Heterogeneity in the Utility of a Surrogate Marker

Biometrics, 2021
Abstract In studies that require long-term and/or costly follow-up of participants to evaluate a treatment, there is often interest in identifying and using a surrogate marker to evaluate the treatment effect. While several statistical methods have been proposed to evaluate potential surrogate markers, available methods generally do not ...
Layla Parast, Tianxi Cai, Lu Tian
openaire   +3 more sources