Results 201 to 210 of about 22,296,575 (338)

DeepSCM: An efficient convolutional neural network surrogate model for the screening of therapeutic antibody viscosity. [PDF]

Comput Struct Biotechnol J, 2022
Lai PK.
europepmc   +1 more source

Surrogate model uncertainty in wind turbine reliability assessment

Renewable Energy, 2020
R. Slot, J. Sørensen, B. Sudret, L. Svenningsen, M. Thøgersen   +4 more
semanticscholar   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Physics-Guided Neural Surrogate Model with Particle Swarm-Based Multi-Objective Optimization for Quasi-Coaxial TSV Interconnect Design. [PDF]

Micromachines (Basel)
Liu Z, Shan G, Chen Z, Yang Y.
europepmc   +1 more source

Novel Approach Using shRNA of IQGAP1 for Colon Cancer Therapy: HCT116 as a Surrogate Model Colorectal Carcinoma [PDF]

Asian Pac J Cancer Prev, 2022
Zoheir KMMA, Mahmoud K, Harisa GI, Ashour A, Abdel-Hamied HE, Amara AA, Mahrous KF, Abd-Rabou AA.   +7 more
europepmc   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Neural network-based surrogate model in postprocessing of topology optimized structures. [PDF]

Neural Comput Appl
Persia JT, Sung MK, Lee S, Burns DE.
europepmc   +1 more source

Next-generation time of death estimation: combining surrogate model-based parameter optimization and numerical thermodynamics. [PDF]

R Soc Open Sci, 2022
Wilk LS, Edelman GJ, Aalders MCG.
europepmc   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Rhodosporidium toruloides-a new surrogate model to study rapamycin induced effects on human aging and cancer. [PDF]

Cell Mol Life Sci
Cavelius PM, Haack M, Awad D, Brueck TB, Mehlmer N.   +4 more
europepmc   +1 more source