Multi-Epitope DNA-Based Feline Immunodeficiency Virus Vaccine Construct Designed by Immunoinformatic and Machine Learning Tools as a Surrogate Model for HIV Vaccine Development. [PDF]
PathogensMichalka T, Shah AU, Liang T, Hemida MG.
europepmc +1 more source
FEBS Open Bio, EarlyView.TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose +9 more
wiley +1 more source
A Heuristic Approach for Surrogate Modelling of Electro-Technical Systems
The optimization of designs of electro-technical systems often is based on expensive calculations (i.e., simulation models). To cut down the cost, surrogate models are constructed from and then used in place of simulations.
Jēkabsons, Gints, Lavendels, Jurijs
core
Speed up Multi-Scale Force-Field Parameter Optimization by Substituting Molecular Dynamics Calculations with a Machine Learning Surrogate Model. [PDF]
ChemphyschemStrickstrock R +3 more
europepmc +1 more source
Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
FEBS Open Bio, EarlyView.Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
wiley +1 more source
A pathology-based surrogate model for chemotherapy decision-making in intermediate-risk luminal breast cancer: validation of histologic grade and Ki67 in a Chinese population. [PDF]
Front Med (Lausanne)Li G, Zeng Y, Sun Y.
europepmc +1 more source
Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region
FEBS Open Bio, EarlyView.Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson +2 more
wiley +1 more source
Multi-marker discovery for mild cognitive impairment in metabolomics using machine learning with a global surrogate model via partial least squares. [PDF]
MetabolomicsTatara Y +8 more
europepmc +1 more source
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
FEBS Open Bio, EarlyView.MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source
A neural network based non-intrusive surrogate modelling framework for fluid-structure interaction
The use of surrogate modelling in Multiphysics simulation is becoming increasingly attractive due to large computation time and hardware demands of modern simulations. These methods aim to reduce the computational time and complexity of the determination
Fairchild, D, Şugar-Gabor, O
core