Results 171 to 180 of about 14,186,820 (252)

Preoperative Planning Framework for Robot-Assisted Dental Implant Surgery: Finite-Parameter Surrogate Model and Optimization of Instrument Placement. [PDF]

Bioengineering (Basel), 2023
Wang Y, Wang W, Cai Y, Zhao Q, Wang Y.
europepmc   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

Aspirin inhibition and recovery of cyclooxygenase activity and thromboxane biosynthesis in human megakaryocytes: a translational surrogate model. [PDF]

J Pharmacol Exp Ther
Mallah ZI, Petrucci G, Ayoub AJ, Farhoud MA, Jelwan JG, Lucchisani S, Fakih AK, Badran B, Hamade E, Patrono C, Rocca B, Habib A.   +11 more
europepmc   +1 more source

A generalised deep learning-based surrogate model for homogenisation utilising material property encoding and physics-based bounds. [PDF]

Sci Rep, 2023
Nakka R, Harursampath D, Ponnusami SA.
europepmc   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Rapid thickness distribution prediction of superplastic formed parts based on geometry adapted PSO-BP neural network surrogate model. [PDF]

Sci Rep
Sun M, Xiong C, Zhou Y, Zhang X, Yuan A, Sun Y, Li Y.   +6 more
europepmc   +1 more source

Tendon Stress Estimation from Strain Data of a Bridge Girder Using Machine Learning-Based Surrogate Model. [PDF]

Sensors (Basel), 2023
Khayam SU, Ajmal A, Park J, Kim IH, Park JW.   +4 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

A GRU-KAN Surrogate Model with Genetic Algorithm Uniform Sampling for Active Magnetic Bearings-Rotor Critical Speed Prediction. [PDF]

Sensors (Basel)
Cui J, Li J, Cai F, Zhao Z, Liu Y.
europepmc   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source