Results 161 to 170 of about 561,088 (291)

Surrogate model-based multi-objective Bayesian optimisation of porous acoustic barriers. [PDF]

Eng Comput
Liravi H, Bécot FX, Kaewunruen S, Ninić J.   +3 more
europepmc   +1 more source

Precision agriculture management based on a surrogate model assisted multiobjective algorithmic framework. [PDF]

Sci Rep, 2023
Cheng D, Yao Y, Liu R, Li X, Guan B, Yu F.   +5 more
europepmc   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Surrogate model for statics of fractional thin bar element and its equivalence with mass-spring metamaterial. [PDF]

Sci Rep
Szajek K, Sumelka W.
europepmc   +1 more source

S.M.A.R.T. F.U.S: Surrogate Model of Attenuation and Refraction in Transcranial Focused Ultrasound. [PDF]

PLoS One, 2022
Cain JA, Visagan S, Monti MM.
europepmc   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Adaptive Planning Method for ERS Point Layout in Aircraft Assembly Driven by Physics-Based Data-Driven Surrogate Model. [PDF]

Sensors (Basel)
Xu S, Huang X, Li S, Hou G.
europepmc   +1 more source

Preoperative Planning Framework for Robot-Assisted Dental Implant Surgery: Finite-Parameter Surrogate Model and Optimization of Instrument Placement. [PDF]

Bioengineering (Basel), 2023
Wang Y, Wang W, Cai Y, Zhao Q, Wang Y.
europepmc   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Aspirin inhibition and recovery of cyclooxygenase activity and thromboxane biosynthesis in human megakaryocytes: a translational surrogate model. [PDF]

J Pharmacol Exp Ther
Mallah ZI, Petrucci G, Ayoub AJ, Farhoud MA, Jelwan JG, Lucchisani S, Fakih AK, Badran B, Hamade E, Patrono C, Rocca B, Habib A.   +11 more
europepmc   +1 more source