Results 241 to 250 of about 24,324,331 (382)

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Optimal control of agent-based models via surrogate modeling. [PDF]

open access: yesPLoS Comput Biol
Fonseca LL   +3 more
europepmc   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

open access: yesFEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe   +5 more
wiley   +1 more source

Evaluation of A Surrogate Contact Model of TKA

open access: yes, 2016
INTRODUCTION: Simultaneous prediction of body-level dynamics and detailed joint mechanics in the frame of musculoskeletal (MS) modeling represents still a highly computationally demanding task. Marra et al. (2014) recently presented and validated a MS model capable of concurrent prediction of muscle forces, knee ligament forces, tibiofemoral (TF) and ...
Marra, Marco   +4 more
openaire   +2 more sources

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