Results 51 to 60 of about 95,160 (289)

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

Human trafficking and surrogate motherhood: challenges

open access: yesКонституційно-правові академічні студії, 2021
  Owing to modern scientific advances prospective parents, among other opportunities, enjoy the opportunity, which has not been available before. It consists in giving birth to a child by using another woman’s reproductive capacity when the situation
Viktor Checherskiy
doaj   +1 more source

Exploratory Analysis of ELP1 Expression in Whole Blood From Patients With Familial Dysautonomia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Familial dysautonomia (FD) is a hereditary neurodevelopmental disorder caused by aberrant splicing of the ELP1 gene, leading to a tissue‐specific reduction in ELP1 protein expression. Preclinical models indicate that increasing ELP1 levels can mitigate disease manifestations.
Alejandra González‐Duarte   +13 more
wiley   +1 more source

Surrogacy with cross-border effects: Reality and law [PDF]

open access: yesZbornik Radova: Pravni Fakultet u Novom Sadu, 2012
This paper analyzes a topic which is highly ranked in law reviews throughout the world, due to the fact that gestational surrogate motherhood as a fact of life is subjected to very different legal regulation worldwide.
Bordaš Bernadet
doaj   +1 more source

Perspektif Hukum Islam Terhadap Anak Yang Dilahirkan Melalui Ibu Pengganti (Surrogate Mother)

open access: yesZaaken, 2023
This study aims to determine and analyze the validity and application of Islamic law perspectives on children born through surrogate mothers. The problems raised are to know how the position of children born through surrogate mothers according to ...
Cindy Yulia Putri   +1 more
doaj   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling   +16 more
wiley   +1 more source

A Blessed Event: How Intended Parents Conceptualize Transnational Surrogacy [PDF]

open access: yes, 2018
This study analyzes the language intended parents (IP) use when they disclose their plans to have a child through surrogacy to their friends and family.
Stoeger, Elizabeth L.
core   +1 more source

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

open access: yes
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana   +8 more
wiley   +1 more source

Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone   +8 more
wiley   +1 more source

An investigation into the psychological well-being of the biological children of surrogates

open access: yesCogent Psychology, 2017
Study Objective: The psychological well-being of surrogates’ own children has not been examined in the US. This study seeks to examine whether having a mother who has served as either a traditional or gestational surrogate impacts the psychological well ...
Mary P. Riddle
doaj   +1 more source

Home - About - Disclaimer - Privacy