Results 101 to 110 of about 18,445 (350)
Surrogate motherhood: ethical or commercial? [PDF]
, 2017 Centre for Social Research
openalex +1 more source
Advanced Science, EarlyView.HiFiCCL, as the first assembly framework specifically designed for low‐coverage high‐fidelity reads, improves the assembly quality of existing assemblers and also enhances downstream applications such as large structural variant (SV) detection (>10 000 bp), synteny analysis, pangenome graph construction, and graph‐based individual‐specific germline SVs
Zhongjun Jiang +9 more
wiley +1 more source
Advanced Science, EarlyView.G9a, and DNA Methyltransferase1 (DNMT1) cooperatively modulates E2F1 on the promoter of tumor suppressor p53‐binding protein 2 (TP53BP2) increased autophagy in preeclampsia. TP53BP2 promotes autophagy in trophoblasts through DNA methylation and H3K9me2‐mediated transcriptional regulation.
Nan Jiang +12 more
wiley +1 more source
Homopaternités et gestation pour autrui
Enfances, Familles, Générations, 2011 This article follows the trajectories of gay fathers who chose to use a surrogate mother in order to become parents. First, we explore the steps leading from the acceptance of homosexuality to the fulfillment of the desire to father a child, examining ...
Martine Gross, Dominique Mehl
doaj
Advanced Science, EarlyView.SLC2A3 derived lactate promotes metastasis through p53 lactylation at K120 and osteoclast differentiation. Pharmacological inhibition of SLC2A3 upregulates PD‐1 expression on CD8+ T cells via lactate induced p53 lactylation, which modulates immune evasion. ABSTRACT Bone metastasis is a devastating consequence of lung cancer.
Yi Ding +10 more
wiley +1 more source
Advanced Science, EarlyView.In trophoblast cells, T/S (TNFα + SM164) activated caspase‐3, which cleaved GSDME to switch apoptosis to pyroptosis, causing cell swelling, membrane rupture, and release of LDH, HMGB1, IL‐1β and IL‐18. These cytokines induced pro‐inflammatory macrophage polarization, which in turn reinforced pyroptotic signaling in trophoblasts, amplifying systemic ...
Baoying Huang +15 more
wiley +1 more source
Surrogate (Replacement) Motherhood or Should the Uterus be Rented?
Pannoniana, 2019 After the birth of the “test-tube baby,” the triumphant success of reproductive technologies has dramatically accelerated scientific research in many fields and given hope to couples struggling with the problem of infertility.
Dejan Donev
doaj
Time‐Efficient and Informatic‐Skill‐Light Gap‐Filling for Telomere‐to‐Telomere Genome Assembly
Advanced Science, EarlyView.The paper introduces a novel auxiliary software toolbox GapSuite, consisting of two tools Gap‐Aid and Gap‐Graph, which guides users to fill gaps in chromosome‐level genome assembly using sequence‐extension‐based and assembly‐graph‐based strategies. The two tools enable users with limited informatics expertise to efficiently complete gap‐filling on ...
Dong Xu +8 more
wiley +1 more source