Results 91 to 100 of about 201,758 (280)

Surrogate motherhood; A regression to a patriarchal society free of social policies?

open access: yesJournal of Modern Science, 2019
Objectives Surrogacy is a very complex issue today, and contrary to what can be believed, and despite the new techniques of human reproduction, gestational surrogacy is not an exclusive practice of the 21st century and Roman law already provides us with ...
Patricia Panero
doaj   +1 more source

Cellular Mechanisms Enabling Mitochondria Transfer and Transplantation

open access: yesAdvanced Science, EarlyView.
Mitochondrial transfer and transplantation (mitoTT) is examined as a multistep process governed by distinct transfer routes and post‐transfer checkpoints. Mechanisms controlling mitochondrial uptake, network integration, cristae remodeling, mtDNA maintenance, immune sensing, and quality control are highlighted, revealing key biological and ...
F. Seyma Gokdemir   +3 more
wiley   +1 more source

Surrogate motherhood conception in the heart

open access: yes, 1994
"Ever since the Baby M case, the public has been fascinated with the continuing phenomenon of surrogate motherhood. The Baby M case raised, and left unanswered, many questions about what constitutes motherhood, fatherhood, family, reproduction, and ...
Ragoné, Helena
core  

Religion, Gender Inequality, and Surrogate Motherhood in Margaret Atwood’s “The Handmaid’s Tale”

open access: yesCoSMO, 2018
Margaret Atwood’s novel The Handmaid’s Tale (1985), is the account of an imaginary future State, the Republic of Gilead, based on strict biblical values where men take back their place as head of the family (and the State), and women go back to their ...
Barbara Miceli
doaj   +1 more source

A Biomimetic cRGDyk‐Engineered Platelet Nanoplatform for ACAD11 Delivery to Trigger Pyroptosis in Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
A biomimetic platelet nanoplatform (OE‐ACAD11@R‐PLT) is developed for targeted hepatocellular carcinoma immunotherapy. By selectively delivering therapeutic plasmids, this system induces mitochondrial dysfunction and triggers robust NLRP3/Caspase‐1/GSDMD‐mediated pyroptosis in tumor cells.
Hongyi Bao   +12 more
wiley   +1 more source

Maternal Hyperglycemia Disrupts Cerebral Cortex Development Through the Foxp1‐Dll1‐Notch Axis

open access: yesAdvanced Science, EarlyView.
Maternal hyperglycemia disrupts offspring cortical development through a Foxp1–Dll1–Notch signaling axis. In a PGDM mouse model, intrauterine hyperglycemia decreases cortical thickness and perturbs neuronal layering by downregulating Foxp1, which transcriptionally regulates the Notch ligand Dll1.
Longkai He   +12 more
wiley   +1 more source

Mitochondrial Quality Control in Degenerative Musculoskeletal Diseases: Signaling Networks and Therapeutic Landscapes

open access: yesAdvanced Science, EarlyView.
Mitochondrial quality control (MQC) collapse redefines osteoarthritis, intervertebral disc degeneration, and osteoporosis as disorders of organelle dysfunction. Damaged mitochondria leak mtDNA and metabolites, driving cGAS‐STING inflammation, epigenetic reprogramming, and metabolic memory.
Haiyang Gao   +7 more
wiley   +1 more source

Establishment History AND Concept OF Surrogate Motherhood

open access: yes, 2020
The article covers the concept of surrogate motherhood, the history of its emergence, formation and development, as well as the general principles and legal nature of the use of surrogate motherhood, the legislation of some countries of the world, and ...
Nuralievich, Y. S. (Yuldashev)
core  

The Right of Abortion in Surrogate Motherhood Arrangements [PDF]

open access: yes, 1987
This article examines whether the right of abortion in the surrogate motherhood context is subject to veto or waiver by contract. After reviewing legislative alternatives to vetoing the surrogate\u27s right to abort, the article concludes that artificial
D\u27Aversa, Carmina Y.
core   +1 more source

LncRNA FLJ20021 Restrains Fibroblast Senescence and Matrix Remodeling in Pelvic Organ Prolapse by Promoting XRCC6‐Dependent ADI1 Transcription

open access: yesAdvanced Science, EarlyView.
FLJ20021 interacts with XRCC6 to regulate ADI1 transcription and downstream cellular phenotypes in hUSLFs. Reduced FLJ20021 in POP is associated with lower ADI1, increased apoptosis, senescence, and an ECM‐degrading marker profile. Conversely, FLJ20021 overexpression enhances XRCC6‐dependent ADI1 expression, reduces apoptosis and senescence, and shifts
YanFeng Yang   +4 more
wiley   +1 more source

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