Results 71 to 80 of about 2,534 (257)

A jurisprudential-medical analysis of the attribution of true dual motherhood in the assumption of a complete surrogate womb [PDF]

open access: yesفقه و حقوق خانواده
Research problem and purpose: The word "mother", a title that is respected and sometimes sanctified in all civilizations. Especially in the moral practice of Islam, mother and the description of motherhood have a unique position and are even considered ...
mostafa keykha   +3 more
doaj   +1 more source

G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis

open access: yesAdvanced Science, EarlyView.
Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang   +9 more
wiley   +1 more source

Dose‐Dependent Reprogramming of Chromatin Accessibility by SOX4 Drives the Transcriptional Response to Iron Overload

open access: yesAdvanced Science, EarlyView.
This study demonstrates that iron overload triggers widespread chromatin compaction and transcriptional repression in human granulosa cells, recapitulating features of endometriosis. The epigenetic reprogramming is orchestrated by a TFEB‐SOX4‐SWI/SNF axis, with SOX4 acting as a central, dosage‐sensitive regulator.
Feifei Li   +15 more
wiley   +1 more source

Stress History Establishes a Transient Tolerant State That Shapes Antibiotic Survival Upon Resuscitation

open access: yesAdvanced Science, EarlyView.
High‐throughput single‐cell analysis of resuscitating bacteria reveals a starvation‐history‐dependent transiently tolerant subpopulation that survives β$\beta$‐lactam exposure by temporarily reducing growth. Distinct from classical persisters, these actively growing yet dynamically modulated cells dominate survival across clinically relevant antibiotic
Kieran Abbott   +5 more
wiley   +1 more source

Vexing Motherhoods in Ireland and Abroad in Nuala Ní Chonchúir’s Mother America [PDF]

open access: yesEstudios Irlandeses, 2018
This article explores the difficulties of representing motherhood from a contemporary – and, allegedly, feminist – perspective in the collection of short stories Mother America (2012) by Irish author Nuala Ní Chonchúir.
Aitor Ibarrola-Armendariz
doaj  

Comparative Responses to Surrogate Motherhood

open access: yes, 1986
I. Introduction II. The Current Status of Surrogate Motherhood ... A. The Basic Transaction ... B. The Legality of Surrogate Motherhood Agreements … 1. Adoption Laws ... a. Prohibiting the Payment of Fees ... b.
Eaton, Thomas A.
core  

Surrogate Motherhood Families /

open access: yes, 2019
This comprehensive book covers the research, theory, policy and practice context of unusual reproduction using third parties. Olga Van den Akker details the psychological adaptation required to continuing changes in public opinion, advances in ...
Van den Akker, Olga B. A.,
core   +1 more source

MEOX1 Coordinates Autocrine‐Paracrine Programs via SPHK1/S1P to Promote Lymph Node Metastasis in Ovarian Cancer

open access: yesAdvanced Science, EarlyView.
In ovarian cancer, MEOX1 activates the SPHK1/S1P pathway to promote both tumor progression and tumor–stroma crosstalk. MEOX1‐dependent signaling drives CAF activation, enhances VEGF‐C expression, and stimulates lymphangiogenesis, ultimately facilitating lymph node metastasis.
Jiajia Li   +10 more
wiley   +1 more source

Surrogate motherhood; A regression to a patriarchal society free of social policies?

open access: yesJournal of Modern Science, 2019
Objectives Surrogacy is a very complex issue today, and contrary to what can be believed, and despite the new techniques of human reproduction, gestational surrogacy is not an exclusive practice of the 21st century and Roman law already provides us with ...
Patricia Panero
doaj   +1 more source

Gasdermin D‐Mediated Release of IL‐33 Results in Fetal Brain Developmental Abnormalities During Maternal Colitis

open access: yesAdvanced Science, EarlyView.
Under colitis, Gsdmd mediates the release of IL‐33 from the epithelium of pregnant mice. IL‐33 can cross the placenta and enhance the proliferative capacity of neural stem cells, ultimately resulting in behavioral deficits in the offspring. Excessive pyroptosis in the colonic epithelium also triggers the translocation of LPS, which in turn increases ...
Huiyang Jia   +4 more
wiley   +1 more source

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