Results 61 to 70 of about 2,534 (257)

Unraveling the Molecular Mechanisms Underlying Spontaneous Multipolar Mitosis Through CIN‐seq

Advanced Science, EarlyView.
Multipolar mitosis, a hallmark of chromosomal instability (CIN), drives tumor heterogeneity but is challenging to study in live cells. Using CIN‐seq, a single‐cell multiomics method, we profiled rare CIN events and identified mechanisms associated with viable multipolar mitosis, including PTEN attenuation, Rho GTPase‐driven cytokinesis failure, and ...
Pin‐Rui Su, Ting‐Chun Chou, Maria Teresa López‐Cascales, Junfeng Huang, Tsai‐Ying Chen, Sjoukje van Wieren, Chan Li, Cecile Beerens, Li You, Jelle Storteboom, Miao‐Ping Chien   +10 more
wiley   +1 more source

Whose Child is This? The Problem of Constructing and Deconstructing Kinship Bonds on the Donor Gamete Market

Интеракция. Интервью. Интерпретация, 2020
Invention and subsequent development of human reproduction technologies allow people to manage reproductive risks, overcome infertility and widen alternative reproductive choice.
Tatyana Yurievna Larkina
doaj   +1 more source

FROM THE FEMINIST DEBATE ON SURROGATE MOTHERHOOD TOWARDS A WOMEN’S HUMAN RIGHTS PERSPECTIVE [PDF]

openThis work of thesis is born from a fruitful starting point for a conversation: is surrogate motherhood a real choice? Are surrogate women correctly protected?
SANTORO, DANIELA
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Zinc Exposure Causes Disulfidptosis to Induce Miscarriage by Up‐Regulating GATA1/METTL1/SLC7A11 Axis

Advanced Science, EarlyView.
Zn exposure up‐regulates GATA1, promoting GATA1‐mediated METTL1 and SLC7A11 transcription. It also enhances METTL1‐mediated m7G modification on SLC7A11 mRNA, increasing SLC7A11 mRNA stability. Ultimately, Zn exposure up‐regulates SLC7A11 at both transcriptional and post‐transcriptional levels, causing disulfidptosis. Knockdown of murine Slc7a11, Gata1,
Wenxin Huang, Yi Sun, Yanxin Wang, Haijun Yan, Xiaoping Yue, Weidong Wu, Xueyu Chen, Jinfang Zhang, Yanbing Lin, Qiong Lei, Nan Ji, Shuaishuai Xing, Liqin Zeng, Qingzheng Kang, Depeng Zhao, Geng Guo, Huidong Zhang   +16 more
wiley   +1 more source

Introduction

, 2003
This is the post print version of the chapter - Copyright @ 2003 The editorsThis book is about surrogacy and, more specifically, surrogate motherhood.
Day Sclater, S, Kaganas, F, Cook, R
core  

Legal regulation of surrogate motherhood

, 2021
The article focuses on the legal aspects of surrogate motherhood and the factors that cause increasing attention to these ...
Khazova O. A.
core  

Adipocyte‐Derived Leptolin Enhances Energy Expenditure and Prevents Obesity

Advanced Science, EarlyView.
We identified a novel adipokine, which we named leptolin. In humans, leptolin levels in white adipose tissue were positively correlated with exercise and negatively associated with body mass index. We observed elevated leptolin in serum from athletes and lower leptolin in serum from obese individuals.
Jiarui Liu, Bingwei Wang, Zhijie Su, Xiaoxv Han, Miao He, Yun Zhao, Yujia Hou, Daotong Li, Weiguang Zhang, Lihua Qin, Ke Wang, Yanchun Li, Yi Yan, Siwang Yu, Xiaoshuai Huang, Tairan Yuwen, Jianyuan Luo, Ruimao Zheng   +17 more
wiley   +1 more source

La problemática constitucional derivada de las técnicas de reproducción humana asistida (TRHA): el caso de la maternidad subrogada // The constitutional problem derived from the assisted reproduction techniques: the case of surrogate motherhood

Revista de Derecho Político, 2017
Resumen: Actualmente el uso de las Técnicas de Reproducción Humana Asistida (TRHA) genera algunos interrogantes y cuestiones no resueltos de manera expresa ni suficiente por una regulación constitucional deficitaria en estas materias. El presente estudio
Gerardo Ruiz Rico
doaj   +1 more source

Establishment History and Concept of Surrogate Motherhood

, 2023
The article covers the concept of surrogate motherhood, the history of its emergence, formation and development, as well as the general principles and legal nature of the use of surrogate motherhood, the legislation of some countries of the world, and ...
Nuralievich, Yuldashev Sherali
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A Toolkit for Targeted Neuromodulation of Striatal Direct Pathway Neurons Rescues Parkinsonian Motor Deficits in Mice

Advanced Science, EarlyView.
An adeno‐associated virus (AAV) toolkit enables selective anatomical and functional targeting of striatal D1‐MSNs through retrograde transduction. Enhanced capsids and engineered enhancers drive robust transgene expression across murine and primate models.
Zexuan Hong, Yujing Zhang, Junjiao Zhang, Hanhe Liu, Qiwei Liu, Yanglei Li, Lixin Yang, Lixia Li, Zhongjie Liu, Zhen Yuan, Zhonghua Lu, Yefei Chen, Yuantao Li, Yuwu Jiang, Taian Liu   +14 more
wiley   +1 more source