Results 151 to 160 of about 480,494 (299)

Surrounding rock control technology of preparation roadway under double-wing mining

Meitan kexue jishu
Aiming at the problem of surrounding rock instability and serious deformation and failure of the preparation roadway in the double-wing mining area, which is affected by the mining superimposed support stress, the stress control technology of the surrounding rock of the preparation roadway in the double-wing mining area is carried out.
Kun WANG, Xiangrui MENG, Guangming ZHAO, Xiang CHENG, Minjie QI, Shikui ZHU   +5 more
openaire   +1 more source

Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2–EZH2–Mediated Microtubule Destabilization

Advanced Science, EarlyView.
This study reveals the mechanism by which chronic hypoxia impairs spermatogenesis via the ASXL2–EZH2 axis, hindering the transition of spermatids from round to elongated forms. Key findings reveal that under hypoxic conditions, downregulated ASXL2 expression reduces EZH2 binding to the CEP162 promoter, leading to decreased H3K27me3 modification and ...
Jun Yin, Mengjie Zhang, Wenying Liu, Wenlong Shen, Debao Li, Hongming Miao, Fang Deng, Gang Zhang, Yi Tian, Yi Zhang, Zhihu Zhao, Bing Ni   +11 more
wiley   +1 more source

Research on the mechanism of deformation and instability of surrounding rock in goaf under dynamic loading and the mechanism of active coordinated control

Frontiers in Earth Science
Dynamic loading from mining activities and surface movements can significantly affect the stability of surrounding rock in goafs, leading to large-scale deformations or even collapses of overlying strata, which may trigger extensive mining disasters and ...
Kun Xu, Kun Xu, Yanlong Chen, Ming Li, Yafei Zhang, Pengjiao Zhang, Tian Chen   +6 more
doaj   +1 more source

Ovarian Matrisome Dynamics and αvβ3‐Mediated Regulation in Early Follicular Development

Advanced Science, EarlyView.
The matrisome undergoes dynamic remodeling during early follicular development. Integrin αvβ3 mediates matrisome signals, regulating primordial follicle activation/atresia and secondary follicle growth via Hippo/mTOR pathways, with conserved roles in human ovaries, offering therapeutic targets for ovarian disorders.
Tong Wu, Yanzhi Feng, Qingqing Zhu, Ting Jiang, Yueyue Gao, Kebing Nie, Xianan Tang, Ying Chen, Dianxing Hu, Xudan Yang, Shixuan Wang, Meng Wu, Jinjin Zhang   +12 more
wiley   +1 more source

Golden Opportunity or False Hope? Anglogold Ashanti's Proposed Gold Mine in the Democratic Republic of Congo [PDF]

, 2010
Deals with the exploitation of resourcesin ...
Sarah Barnett
core  

Cellular Snowballing: Cell Adhesion and Migration Drive the Self‐Assembly of Cell‐Microgel Biohybrid Spheroids

Advanced Science, EarlyView.
A new class of biohybrid spheroids is engineered through the self‐assembly of adherent cells and extracellular matrix‐mimetic hydrogel microparticles (microgels). By mimicking a snowballing effect, this approach enables scalable formation of porous, millimeter‐scale spheroids with enhanced cell viability and molecular diffusion.
Zaman Ataie, Sina Kheirabadi, Changhao Li, Aneesh Risbud, Aswathy Sebastian, Istvan Albert, Sulin Zhang, Amir Sheikhi   +7 more
wiley   +1 more source

Microbial Effects on Repository Performance [PDF]

, 2010
This report presents a critical review of the international literature on microbial effects in and around a deep geological repository for higher activity wastes.
Humphreys, Paul, Metcalfe, R., West, J. M.   +2 more
core  

Unraveling the Molecular Mechanisms Underlying Spontaneous Multipolar Mitosis Through CIN‐seq

Advanced Science, EarlyView.
Multipolar mitosis, a hallmark of chromosomal instability (CIN), drives tumor heterogeneity but is challenging to study in live cells. Using CIN‐seq, a single‐cell multiomics method, we profiled rare CIN events and identified mechanisms associated with viable multipolar mitosis, including PTEN attenuation, Rho GTPase‐driven cytokinesis failure, and ...
Pin‐Rui Su, Ting‐Chun Chou, Maria Teresa López‐Cascales, Junfeng Huang, Tsai‐Ying Chen, Sjoukje van Wieren, Chan Li, Cecile Beerens, Li You, Jelle Storteboom, Miao‐Ping Chien   +10 more
wiley   +1 more source

Stability analysis and control countermeasures of surrounding rock of gob-side entry formed by roof-cutting in inclined coal seams

Energy Exploration & Exploitation
The stability of the surrounding rock in the inclined coal seam stope is crucial for the safety of the gob-side entry. In this article, we systematically analyze the surrounding rock stability of the gob-side entry formed by roof-cutting (GEFR) in an ...
Enze Zhen, Shizhuo Dong, Xiaowei Xu, Yajun Wang, Mengxiang Wang   +4 more
doaj   +1 more source

In Situ Characterisation of Hydrogels via Dynamic Interface Printing

Advanced Science, EarlyView.
ABSTRACT Hydrogels have become pivotal materials for tissue engineering, robotics, biomedical devices, and sensing applications due to their diverse material compositions and tunable mechanical properties. While significant effort has focused on developing novel manufacturing approaches such as extrusion bioprinting and light‐based fabrication methods,
Callum Vidler, Michael Halwes, David J. Collins   +2 more
wiley   +1 more source