Results 161 to 170 of about 121,917 (257)

Single‐Cell Profiling Identifies CLEC5A+ Macrophages as Key Drivers of Thoracic Aortic Aneurysm Via CCL5‐Mediated M1 Polarization

Journal of Clinical Laboratory Analysis, EarlyView.
Thoracic aortic aneurysm (TAA) is a life‐threatening cardiovascular disease with limited therapeutic options. Through single‐cell RNA sequencing of aortic tissues from healthy individuals and TAA patients (105,541 cells), we identified CLEC5A+macrophages as the predominant pathogenic cell population exhibiting the highest M1 polarization score. Machine
Xiangyu Li, Chunguang Guo, Mingyao Luo, Chang Shu   +3 more
wiley   +1 more source

Neisseria gonorrhoeae Sequence Type 16676 in Disseminated Infections, Minnesota, USA, 2025. [PDF]

Emerg Infect Dis
Evans D, LaPointe A, Peel C, Bo-Subait K, Dufort E, Stewart J, Kaiyalethe J, Craft B, Plumb M, Weber B, Bohnker-Voels L, Pung K, Mondelli A, Garfin J, Namugenyi S, Snippes-Vagnone P, Gyllstrom ME, Como-Sabetti K, Lynfield R.   +18 more
europepmc   +1 more source

Molecular Functions and Drug Prediction of MMP1 and TGFBR2 in Nasopharyngeal Carcinoma

Journal of Clinical Laboratory Analysis, EarlyView.
MMP1 and TGFBR2 were validated by machine learning and external datasets as the candidate genes. Dexamethasone showed strong binding affinity to MMP1 (−7.72 kcal/mol) and TGFBR2 (−7.27 kcal/mol) in docking studies. Knockdown of MMP1 repressed the malignant phenotypes of NPC cells.
Feng Wang, Binbin Ge, Ming Li, Xiaochun Xia, Fuming Zhang, Pengqin Xu   +5 more
wiley   +1 more source

CDC Operational Guidance for Investigating Locally Acquired Mosquito-Transmitted Malaria - United States, 2026. [PDF]

MMWR Recomm Rep
Ranadive N, Barratt JLN, Dotson EM, Gimnig JE, Lenhart AE, Levine RS, Mace KE, McElroy PD, Raphael BH, Sayre D, Steinhardt LC, Sutcliffe AC, Williams SG, Ridpath AD.   +13 more
europepmc   +1 more source

A Small‐Scale Regional External Quality Assessment of Nucleic Acid Amplification Tests for Bordetella pertussis in China

Journal of Clinical Laboratory Analysis, EarlyView.
An external quality assessment (EQA) was conducted to evaluate the performance of nucleic acid amplification tests (NAATs) for Bordetella pertussis across 69 laboratories in Chongqing, China. Among 345 total reports, 341 (98.8%) were concordant with expected results, while four false negatives occurred in low‐concentration samples near the analytical ...
Yuanyuan Guo, Junjiang Zhou, Zhijie Li, Jiangming Xiao, Tian Li, Changchun Niu, Yang Luo   +6 more
wiley   +1 more source

Understanding spatiotemporal clustering of seasonal influenza in the United States. [PDF]

BMC Infect Dis
Chan LYH, Morris S, Hassell N, Marcenac P, Couture A, Colon A, Kniss K, Budd A, Biggerstaff M, Borchering R.   +9 more
europepmc   +1 more source

Diagnostic Performance of Direct PCR Assay for Candida auris Detection: A Comparison of Liquid Amies Transport Medium and Fungal Enrichment Broth

Journal of Clinical Laboratory Analysis, EarlyView.
This study evaluated a direct PCR assay for rapid Candida auris screening from skin swabs using two transport media. The direct PCR assay demonstrated high sensitivity (92.0%–96.0%) and rapid turnaround time (~3 h). Liquid Amies medium showed a more favorable specificity profile, supporting its practical utility for screening.
Jung‐ah Kim, Yu Kyung Jeon, Eun Jeong Won, Heungsup Sung, Mi‐Na Kim   +4 more
wiley   +1 more source

Surveillance of tick-borne pathogens in ticks collected from Swiss residents. [PDF]

Parasit Vectors
Ghasemian E, Marquis B, Tagini F, Aeby S, Tischhauser W, Lienhard R, Beuret C, Martin V, Hälg S, Müller P, Croxatto A, Opota O, Greub G.   +12 more
europepmc   +1 more source

Clinical progress note: Rotavirus

Journal of Hospital Medicine, EarlyView.
Abstract Rotavirus is a vaccine‐preventable cause of acute, viral gastroenteritis typically characterized by diarrhea, vomiting, and fever. Prior to rotavirus vaccine introduction, nearly all children worldwide had been infected by 5 years of age. Severe rotavirus gastroenteritis causes dehydration and electrolyte derangements, and infants and young ...
Kelsey Thetford, Meghan Hofto
wiley   +1 more source

National surveillance of antimicrobial resistance in Iran using IAMR software: A hospital-based study. [PDF]

New Microbes New Infect
Hoseinzadeh E, Masoumi-Asl H.
europepmc   +1 more source