Results 211 to 220 of about 1,413,891 (296)

Antimicrobial Resistance in Extragenital Neisseria gonorrhoeae Infections, US Military Centers, 2022-2024. [PDF]

Emerg Infect Dis
Dombach JL, MacArthur JL, Mekonnen C, Au La TH, Nxedhlana V, Norris MH, Smith HJ, Copeland NK, Kamau E.   +8 more
europepmc   +1 more source

Clearance of high‐risk human papillomavirus in patients with cervical intraepithelial neoplasia 2–3 after the loop electrosurgical excision procedure with negative resection margins

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective This study aims to evaluate the longitudinal clearance rates of high‐risk human papillomavirus (hr‐HPV) and the incidence of clinical recurrence (defined by abnormal cytology or histologically confirmed cervical intraepithelial neoplasia; CIN) at 6 and 18 months post‐loop electrosurgical excision procedure (LEEP), characterizing the ...
Praew Sittichivapak, Pattama Chaopotong
wiley   +1 more source

Cysteine Peptidases in Antitumor Immunity: Unraveling Antigen‐Presenting Cell Regulation and Therapeutic Potential

iMetaMed, EarlyView.
This review systematically summarizes the central role of cysteine peptidases in modulating antigen‐presenting cell (APC) function and antitumor immune responses, highlighting their critical significance in overcoming tumor immune evasion. Current research has established that cysteine peptidase subtypes, including cathepsins B, S, L, and X, exert ...
Yimao Wu, Xiaoyan Chen, Zichang Chen, Yalun Liang, Gokhan Zengin, Qian Zhang, Wenlong Sun, Meng‐Yao Li   +7 more
wiley   +1 more source

Automated detection and classification of intestinal protozoan cysts using a nuclei structure-based deep learning framework for epidemiological surveillance. [PDF]

Parasite Epidemiol Control
Tsai JC, Chen YR, Tan SM, Jin KL, Wu CC, Lai JH, Huang KL, Chu CC, Hung SH, Lin JY, Bal SS, Yang FP, Lee KS, Chen TW, Hung CH, Liang CC, Tsai HJ, Chen IP, Li CH, Hsieh YN, Tsai CL.   +20 more
europepmc   +1 more source

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

Development and clinical validation of a colorimetric isothermal assay for rapid detection of monkeypox virus. [PDF]

New Microbes New Infect
Nandi SS, Sawant SA, Yadav P, Shete-Aich A, Majumdar TD, Bavkar KC, Mukherjee A, Deshpande JM.   +7 more
europepmc   +1 more source

Microbial metabolite indole‐3‐propionic acid preserves astrocytic mitochondrial mitofusin 2 to limit neuroinflammation after traumatic brain injury

Interdisciplinary Medicine, EarlyView.
Following traumatic brain injury, indole‐3‐propionic acid (IPA) directly targets the aryl hydrocarbon receptor on astrocytes in the peri‐lesional cortex; this suppresses interferon regulatory factor 1‐driven transcription of the E3 ubiquitin ligase RFFL (ring finger and FYVE‐like domain containing E3 ubiquitin protein ligase).
Ziwen Zhang, Kai Wang, Liangbo Wang, Wencong Li, Hao Guo, Meng Xu, Tinghao Wang, Jiahui Ren, Ting Zhu, Jiahui Wang, Wenxing Cui, Jinpeng Zhou, Yang Tian, Liying Han, Chengxuan Guo, Shuoyao Ma, Qiang Wang, Zhihong Li, Yaning Cai, Jingyu Dong, Xun Wu, Haixiao Liu, Yan Qu   +22 more
wiley   +1 more source

Epidemiological and Molecular Characterization of Human Metapneumovirus (HMPV) in Children Under 14 Years of Age in Shijiazhuang City, China. [PDF]

Pathogens
Li S, Jiang C, Geng M, Guo N, Wu W, Pang Z, Zhou X, Xue J, Bian Y, Jia J, Han X, Li Y, Li Q.   +12 more
europepmc   +1 more source

Enhanced CRISPR‐cas systems for genome editing and molecular diagnostics

Interdisciplinary Medicine, EarlyView.
This review systematically summarizes the major optimization strategies for CRISPR‐Cas systems, focusing on the engineering of Cas proteins, guide RNAs, reporter probes, and the incorporation of chemical additives. The aim is to enhance editing precision and diagnostic capability, thereby expanding the CRISPR system's potential for broader biomedical ...
Sheng Li, Han Li, Bojie Chen, Ling Jiang, Keyu Long, Jiaqi Lang, Xingxiang Pu, Erhu Xiong   +7 more
wiley   +1 more source

Bacterial Meningitis Epidemiology in Burkina Faso and Niger-High-Risk Countries in the Meningitis Belt of Sub-Saharan Africa, 2015-2023. [PDF]

J Infect Dis
Pinell-McNamara VA, Ouédraogo HS, Kafando L, Sani O, Issoufou AA, Tassiou EI, Sanou M, Tarbangdo F, Bita A, Fernandez K, Kekeisen-Chen J, Cureau N, Aboubacar A, Acho F, Aké F, Childs L, Farrar JL, Gbaguidi CAP, Kambou F, Katsande R, Kobayashi M, Latt A, Lingani C, Marjuki H, McGee L, Neatherlin J, Novak RT, Ouattara M, Pezzoli L, Soeters HM, Tonde I, Tamboura M, Mamane Z, Yameogo I, McNamara LA.   +34 more
europepmc   +1 more source