Results 101 to 110 of about 1,321,168 (316)

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Crime, security and surveilance: effects for the surveillant and the surveilled

, 2012
The surveillance society has significantly been discussed in social sciences over the last ten years. Phenomena like terrorist threats and illegal migration flows on the one hand and an anxious western population on the other seems to legitimize a considerable growth and sophistication of databases and surveillance technologies.
Vande Walle, Gudrun, Van den Herrewegen, Evelien, Zurawski, Nils   +2 more
openaire   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Studying Surveillance in Greece: Methodological and Other Problems Related to an Authoritarian Surveillance Culture [PDF]

, 2002
Using the example of Greek society this paper documents how the pragmatics and practicalities of \u27doing surveillance studies\u27 can itself be shaped by the unique political and social history of the society being studied.
Samatas, Minas
core  

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Recursive Surveillance and the Persistence of Authoritarian Surveillance in Brazil [PDF]

To comprehend contemporary surveillance in Brazil, especially under Bolsonaro’s administration (2019–2022), it is crucial to revisit the country’s most authoritarian period, the military dictatorship (1964–1985).
Melgaço, Lucas
core  

Editorial: Platform Surveillance [PDF]

, 2019
This editorial introduces this special responsive issue on “platform surveillance.” We develop the term platform surveillance to account for the manifold and often insidious ways that digital platforms fundamentally transform social practices and ...
Monahan, Torin, Murakami Wood, David
core  

Effects on Intestinal Mucosal Morphology, Productive Parameters and Microbiota Composition after Supplementation with Fermented Defatted Alperujo (FDA) in Laying Hens

Antibiotics, 2019
The olive oil sector is currently adapting its traditional function to also become a supplier of high-value by-products that possess antioxidant, anti-inflammatory and antimicrobial properties.
Agustín Rebollada-Merino, Carmen Bárcena, María Ugarte-Ruiz, Néstor Porras, Francisco J. Mayoral-Alegre, Irene Tomé-Sánchez, Lucas Domínguez, Antonio Rodríguez-Bertos   +7 more
doaj   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source