Results 91 to 100 of about 1,321,168 (316)

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Primary leptomeningeal histiocytic lymphoproliferative disorder associated with SARS-CoV-2 brain infection in k18-hACE2 mouse: a case report

open access: yesLaboratory Animal Research
Background Histiocytic proliferative disorders in the central nervous system are rare, and their potential association with viral infections remains largely unexplored.
Néstor Porras   +4 more
doaj   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

open access: yesMolecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant   +7 more
wiley   +1 more source

Protesters’ Reactions to Video Surveillance of Demonstrations: Counter-Moves, Security Cultures, and the Spiral of Surveillance and Counter-Surveillance [PDF]

open access: yes, 2018
This article analyses protesters’ reactions to police video surveillance of demonstrations in Germany. Theoretically, we draw on the concept of a “spiral of surveillance and counter-surveillance” to understand the interaction processes which ...
Knopp, Philipp, Ullrich, Peter
core  

Facing Surveillance: Personified Surveillance, Algorithmic Injustice, and the Myth of Big Brother in Post-Snowden Popular Culture [PDF]

open access: yes, 2022
This article examines an archive of recent films, fiction, and interactive media that use personified representations of surveillance to depict and critique real-world surveillance practices.
Kelly, Nicholas
core  

National Near Real-Time Vaccine Effectiveness Against COVID-19 Severe Outcomes Using the Screening Method Among Older Adults Aged ≥50 Years in Canada

open access: yesVaccines
Background/Objectives: It is critical to monitor real-world COVID-19 vaccine effectiveness (VE) in older adults, as they have been identified as a priority group for vaccination.
Robert MacTavish   +10 more
doaj   +1 more source

Antemortem diagnosis of human rabies in a veterinarian infected when handling a herbivore in Minas Gerais, Brazil

open access: yesRevista do Instituto de Medicina Tropical de São Paulo, 2011
The Ministry of Health's National Human Rabies Control Program advocates pre-exposure prophylaxis (PEP) for professionals involved with animals that are at risk of contracting rabies.
Mariana Gontijo de Brito   +8 more
doaj   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

Humanitarian and Human Rights Surveillance: The Challenge to Border Surveillance and Invisibility? [PDF]

open access: yes, 2019
The European border regime has traditionally rested on the hidden surveillance activities of border authorities, which have contributed to human rights violations (including “push-back” and “left-to-die” practices) and a rising migrant death toll ...
Topak, Özgün E.
core  

Smart Cities as Surveillance Theatre [PDF]

open access: yes, 2021
In this opinion piece, we challenge the dominating view that surveillance in smart cities is driven by surveillance capitalism alone. Whilst this literature unpicks important factors and trends, we argue that a focus on surveillance capitalism as a sole ...
Melgaço, Lucas, van Brakel, Rosamunde
core  

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