Results 91 to 100 of about 1,321,168 (316)
PANoptosis in the pathogenesis of myelodysplastic syndromes
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Background Histiocytic proliferative disorders in the central nervous system are rare, and their potential association with viral infections remains largely unexplored.
Néstor Porras +4 more
doaj +1 more source
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant +7 more
wiley +1 more source
Protesters’ Reactions to Video Surveillance of Demonstrations: Counter-Moves, Security Cultures, and the Spiral of Surveillance and Counter-Surveillance [PDF]
This article analyses protesters’ reactions to police video surveillance of demonstrations in Germany. Theoretically, we draw on the concept of a “spiral of surveillance and counter-surveillance” to understand the interaction processes which ...
Knopp, Philipp, Ullrich, Peter
core
Facing Surveillance: Personified Surveillance, Algorithmic Injustice, and the Myth of Big Brother in Post-Snowden Popular Culture [PDF]
This article examines an archive of recent films, fiction, and interactive media that use personified representations of surveillance to depict and critique real-world surveillance practices.
Kelly, Nicholas
core
Background/Objectives: It is critical to monitor real-world COVID-19 vaccine effectiveness (VE) in older adults, as they have been identified as a priority group for vaccination.
Robert MacTavish +10 more
doaj +1 more source
The Ministry of Health's National Human Rabies Control Program advocates pre-exposure prophylaxis (PEP) for professionals involved with animals that are at risk of contracting rabies.
Mariana Gontijo de Brito +8 more
doaj +1 more source
Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
Humanitarian and Human Rights Surveillance: The Challenge to Border Surveillance and Invisibility? [PDF]
The European border regime has traditionally rested on the hidden surveillance activities of border authorities, which have contributed to human rights violations (including “push-back” and “left-to-die” practices) and a rising migrant death toll ...
Topak, Özgün E.
core
Smart Cities as Surveillance Theatre [PDF]
In this opinion piece, we challenge the dominating view that surveillance in smart cities is driven by surveillance capitalism alone. Whilst this literature unpicks important factors and trends, we argue that a focus on surveillance capitalism as a sole ...
Melgaço, Lucas, van Brakel, Rosamunde
core

