Results 71 to 80 of about 1,596,455 (296)

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Surveillance Chess

, 2014
Surveillance Chess Hijacking CCTV Cameras in London London. On the brink of the Olympic Games. Equipped with an interfering transmitter the authors hack surveillance cameras in London and assume control.
Bitnik, !Mediengruppe
core   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

The real-time infection hospitalisation and fatality risk across the COVID-19 pandemic in England

Nature Communications
The COVID-19 pandemic led to 231,841 deaths and 940,243 hospitalisations in England, by the end of March 2023. This paper calculates the real-time infection hospitalisation risk (IHR) and infection fatality risk (IFR) using the Office for National ...
Thomas Ward, Martyn Fyles, Alex Glaser, Robert S. Paton, William Ferguson, Christopher E. Overton   +5 more
doaj   +1 more source

The multifaceted roles of lysosomes in cancer

Molecular Oncology, EarlyView.
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley   +1 more source

Genomic epidemiology of Mycobacterium tuberculosis in Wales

Scientific Reports
Identification of factors contributing to tuberculosis (TB) transmission can guide targeted measures to reduce morbidity. Varying findings for factors associated with TB genomic clustering exist.
Nicole Pacchiarini, Felicity Simkin, Mark Postans, George Ahern, Jiao Song, Clare Brown, Josie Smith, Catie Williams, Matthijs Backx, Daniel Thomas, Thomas R. Connor, Christopher Williams   +11 more
doaj   +1 more source

Weekly Influenza Surveillance Report Week 40 2004: Week starting Monday 27th September 2004 & ending Sunday 3rd October 2004

, 2004
Welcome to the first influenza surveillance report of the 2004/2005-influenza season. This is the fifth season of influenza surveillance using computerised sentinel general practices in Ireland.
National Disease Surveillance Centre (NDSC), National Virus Reference Laboratory (NVRL), Irish College of General Practitioners (ICGP)   +2 more
core  

Just Surveillance? Towards a Normative Theory of Surveillance

, 2014
Despite recent growth in surveillance capabilities there has been little discussion regarding the ethics of surveillance.  Much of the research that has been carried out has tended to lack a coherent structure or fails to address key concerns.
Macnish, Kevin
core   +1 more source

Attitudes of cancer patients toward ctDNA‐based liquid biopsy for follow‐up

Molecular Oncology, EarlyView.
This mixed‐methods study explored cancer patients' experiences, knowledge, and preferences regarding ctDNA‐based liquid biopsy for follow‐up. Awareness of ctDNA was low and recall of previous liquid biopsy was imperfect, yet acceptance was high.
Siddharth Chhajlani, Laura Mariën, Caro De Weerdt, Sanne Wouters, Laure‐Anne Teuwen, Hans Prenen, Katleen Janssens, Timon Vandamme   +7 more
wiley   +1 more source

Surveillance is Sexy

, 2009
This paper considers sexualization of surveillance as a mode of resistance. It explores various modes of sexualized surveillance, from ‘reality porn’ to webcam footage, and focuses on the ways in which voyeurism and exhibitionism are mobilized within an ...
Bell, David
core