Results 101 to 110 of about 1,617,498 (307)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Placebo by proxy expectations toward acupuncture change over time: a survey comparing parental expectations to acupuncture pre- and postoperatively

BMC Complementary and Alternative Medicine, 2018
Background Patients entering a treatment have expectancy to outcome based on their previous experience, the information received, and the credibility of the treatment.
Ingrid Liodden, Are Hugo Pripp, Arne Johan Norheim   +2 more
doaj   +1 more source

On the forecast accuracy and consistency of exchange rate expectations: The Spanish PwC Survey [PDF]

We examine the predictive ability and consistency properties of exchange rate expectations for the dollar/euro using a survey conducted in Spain by PwC among a panel of experts and entrepreneurs.
Maria del Carmen Ramos-Herrera, Simón Sosvilla-Rivero   +1 more
core  

Retirement expectations, pension reforms and their impact on private wealth accumulation [PDF]

, 2006
We estimate the effect of pension reforms on households' expectations of retirement outcomes and private wealth accumulation decisions exploiting a decade of intense Italian pension reforms as a source of exogenous variation in expected pension wealth ...
Attanasio, Bernheim, Bernheim, Bernheim, Boeri, Brandolini, Brugiavini, Feldstein, Feldstein, Gale, Gruber, Gruber, Gustman, Gustman, Hurd, Jappelli, Lusardi, Mario Padula, Mitchell, Renata Bottazzi, Rossi, Thaler, Tullio Jappelli, White   +23 more
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Money Illusion and Rational Expectations: New Evidence from Well Known Survey Data [PDF]

This paper provides further evidence in favor of less than fully rational expectations by making use two instruments, one quite well known, and the other more novel, namely survey data on inflation expectations and Smooth Transition Error Correction ...
Novella Maugeri
core  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Quantification of Ordinal Surveys and Rational Testing: An Application to the Colombian Monthly Survey of Economic Expectations Cuantificación de encuestas ordinales y pruebas de racionalidad: una aplicación con la encuesta mensual de expectativas económicas

Revista Colombiana de Estadística, 2012
Expectations and perceptions obtained in surveys play an important role in designing the monetary policy. In this paper we construct continuous variables from the qualitative responses of the Colombian Economic Expectation Survey (EES).
MARGARITA MARÍN, KATHERINE SÁNCHEZ, HÉCTOR MANUEL ZÁRATE   +2 more
doaj  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

The New Keynesian Phillips Curve and the Role of Expectations: Evidence from the Ifo World Economic Survey [PDF]

We provide evidence on the fit of the hybrid New Keynesian Phillips curve for selected euro zone countries, the US and the UK. Instead of imposing rational expectations and estimating the Phillips curve by the Generalized Method of Moments, we follow ...
Steffen Henzel, Timo Wollmershäuser
core