Results 181 to 190 of about 89,205 (311)

Research priority setting for unpaid carers of older adults, patients with palliative care needs and at the end of life in Australia. [PDF]

Palliat Care Soc Pract
Javanparast S, Martin P, Dullow A, Willis A, Omoya O, Tieman J.   +5 more
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Review of Survey activities 2016: Structures and stratigraphy of Danian limestone, eastern Sjælland, Denmark [PDF]

Geological Survey of Denmark and Greenland Bulletin, 2017
P.R. Jakobsen, M.M. Rohde, E. Sheldon
doaj  

Organisational readiness and preparedness for trauma-informed practice across UK frontline services: a mixed-methods study. [PDF]

Eur J Psychotraumatol
Cogan N, Whittaker S, Kirk A, Hodgson W, Rasmussen S, Short C.   +5 more
europepmc   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Review of Survey activities 2016: Prospectivity mapping for orogenic gold in South-East Greenland, Electronic Supplement Figs. ES1-ES3 [PDF]

Geological Survey of Denmark and Greenland Bulletin, 2017
B.H. Heincke, B.M. Stensgaard
doaj  

Research priorities for oral health in people with severe mental ill-health. [PDF]

BMJ Ment Health
Joury E, Heidari E, Tracy D, Barngkgei I, Shiers D, Johnston G, Bhui K.   +6 more
europepmc   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Review of Survey activities 2013: Surface albedo as a proxy for the mass balance of Greenland’s terrestrial ice [PDF]

Geological Survey of Denmark and Greenland Bulletin, 2014
Colgan, W., Box, J.E., Fausto, R.S, van As, D., Barletta, V.R., Forsberg, R.   +5 more
doaj  

Innovative technologies and workplace collaborations in the energy sector based in the United Arab Emirates. [PDF]

Front Artif Intell
Boath JC, Gilani SAM, Tiemo TH, Tantry A.   +3 more
europepmc   +1 more source