Results 231 to 240 of about 89,205 (311)

What Matters Most: The Top 10 Child and Adolescent Cancer Research Priorities in Australia. [PDF]

Health Expect
De Silva G, Robertson EG, Bowers A, Schilstra C, Patel SK, McCarthy MC, McLoone J, Pole JD, Sansom-Daly UM, Oppelaar S, Cummings J, Bradford N.   +11 more
europepmc   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Review of Survey activities 2015: New zircon U-Pb and Hf isotopic constraints on the crustal evolution of the Skjoldungen region, South-East Greenland [PDF]

Geological Survey of Denmark and Greenland Bulletin, 2016
T.F. Kokfelt, T. Næraa, K. Thrane, L. Bagas   +3 more
doaj  

Australian healthcare workers' perspectives, practices, and perceived barriers to a more environmentally sustainable health system: a cross-sectional survey. [PDF]

BMC Health Serv Res
Loftus MJ, Lokmic-Tomkins Z, Eades O, Asghari-Jafarabadi M, Walker-Bone K, Chee A, Davies J, Dunne B, Ellis X, Forrester M, Gemmell M, Hii MW, Hutchinson A, Kiang KM, McIntyre K, Roberts LJ, Russo PL, Sohail A, McGuinness SL, Leder K.   +19 more
europepmc   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Review of Survey activities 2013: Earthquake swarms in Greenland [PDF]

Geological Survey of Denmark and Greenland Bulletin, 2014
Larsen, T.B., Voss, P.H., Dahl-Jensen, T., Rasmusen, H.P.   +3 more
doaj  

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Review of Survey activities 2016: Greenland, Canadian and Icelandic land-ice albedo grids (2000–2016) [PDF]

Geological Survey of Denmark and Greenland Bulletin, 2017
J.E. Box, D. van As, K. Steffen , PROMICE project team   +3 more
doaj  

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

A Baseline Quantitative Analysis of Technology-Facilitated Gender-Based Violence Against Women with Disabilities in South Africa. [PDF]

Behav Sci (Basel)
Ned L, Tyabashe-Phume B, Tunggal E, Soldatić K.   +3 more
europepmc   +1 more source