Results 141 to 150 of about 3,992,788 (314)

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

November 2023 international forum on species in Haikou, China

Oryx
Yan Xie, Amaël Borzée, Kit-Yue Kwan, John MacKinnon, Haichao Zhou, Eric Ameca, Cristian Bonacic, Bo Cai, Topiltzin Contreras-MacBeath, Keith Crandall, Alok Das, Abraham Desalegn, Maximin Djondo, Weidong Li, Gregory Mueller, Serigne Sarr, Meta Sindani, Manfredo Turcios-Casco, Xinquan Zhao   +18 more
doaj   +1 more source

Liver Transplantation for HBV-Related Disease in France: NUC Type Before LT Is Associated With Patient Survival. [PDF]

Liver Int
Bienvenue I, Roux O, Coilly A, Abergel A, Antonini T, Artzner T, Boillot O, Chermak F, Conti F, Dharancy S, Duvoux C, Elkrief L, Farrugia M, Francoz C, Giguet B, Hardwigsen J, Houssel-Debry P, Hilleret MN, Kamar N, Latournerie M, Meszaros M, Radenne S, Roche B, Salamé E, Verhoeven-Weil D, Samuel D, Zoulim F, Dumortier J, Villeret F.   +28 more
europepmc   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

Confidence bands for the survival function [PDF]

In several medical reports, the survival function is graphed along with the confidence intervals. The endpoints of the confidence intervals are usually connected to draw an area where the entire survival curve is contained with a given confidence ...
Enzo Coviello
core  

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Age, Age-Related Comorbidities and Survival in Palbociclib, Ribociclib and Abemaciclib Users With Advanced Breast Cancer: A Nation-Wide Retrospective Cohort Study. [PDF]

Pharmacoepidemiol Drug Saf
Rajamaki B, Tenhunen O, Pylkkänen L, Vo T, Paakinaho A, Turpeinen M, Hartikainen S, Tolppanen AM.   +7 more
europepmc   +1 more source

Surviving survival analysis [PDF]

Bone Marrow Transplantation, 2001
openaire   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Robust Likelihood-Based Survival Modeling with Microarray Data

Gene expression data can be associated with various clinical outcomes. In particular, these data can be of importance in discovering survival-associated genes for medical applications.
HyungJun Cho, Sukwoo Kim, Ami Yu, Jaewoo Kang, Seung-Mo Hong   +4 more
core