Results 141 to 150 of about 4,475,446 (306)
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Transport to Hospital Without Sustained Return of Spontaneous Circulation After Out-of-Hospital Cardiac Arrest: Outcomes From Western Australia. [PDF]
Emerg Med AustralasMajewski D, Belcher J, Ball S, Finn J.
europepmc +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Daily activities and survival at older ages [PDF]
This study tested the hypothesis that time spent on regenerative (e.g., resting), productive (e.g., housework), and consumptive activities (e.g., meeting friends) is associated with survival in persons aged 70 and older.
Petra L. Klumb, Heiner Maier
core
TAUS: Target-Age Unified Survival. Survival Analysis Without Assuming Proportional Hazards or Parameterising the Survival Function. [PDF]
Ecol EvolCasas Gomez-Uribarri I +4 more
europepmc +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Reinstatement of the Anoline Lizard Specialist Group: a renewed commitment to conservation
OryxAnna Thonis +5 more
doaj +1 more source
Racial and ethnic survival disparities in primary liver cancer in the United States: a National Cancer Database propensity score-matched study. [PDF]
Hepat OncolOzer M +8 more
europepmc +1 more source