Results 161 to 170 of about 4,616,179 (262)

Predicting median survival times from early data in immunotherapy trials using exponential-decay modeling. [PDF]

J Natl Cancer Inst
Opperman T, Patel R, Chiong JD, Stewart DJ, Nasser A.   +4 more
europepmc   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Introducing the Seaweed Specialist Group of the IUCN Species Survival Commission

Oryx
Nur Arafeh-Dalmau, Erlania, Emma Cebrian, Loyiso V. Dunga, Paulo Horta, Cayne Layton, Erasmo C. Macaya, Luisa Mangialajo, Pippa J. Moore, Alejandra Mora-Soto, Maggie M. Reddy, Albertus J. Smit, Pike Spector, Van Tu Nguyen, Jana Verdura, Jacqueline B. Pocklington   +15 more
doaj   +1 more source

MGP_HNSC32: A H&E Morphology-Derived 32-Gene Prognostic Signature in Head and Neck Squamous Cell Carcinoma. [PDF]

Cancer Med
Zhao D, Huang Z, Xu J, Zhang Z, Hess J, Feng B.   +5 more
europepmc   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

First study on the survival and dispersal of captive-reared narrow-headed softshell turtles along the Yamuna River, India

Oryx
Arunima Singh, Shailendra Singh, Adarsh Kumar, Pawan Shantiprakash Pareek, Sreeparna Dutta   +4 more
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Turning the tide for sharks: Important Shark and Ray Areas

Oryx
Asia O. Armstrong, Amanda Batlle-Morera, Vanessa Bettcher Brito, Ryan Charles, Emiliano García-Rodríguez, Adriana Gonzalez-Pestana, Peter M. Kyne, Giuseppe Notarbartolo di Sciara, Marta D. Palacios, Christoph A. Rohner, Rima W. Jabado   +10 more
doaj   +1 more source

A data-constrained survival stratification model for surgically managed glioblastoma across public and real-world cohorts. [PDF]

Front Oncol
Zeng L, Li D, Liao Y, Du M, Wu T, Huang Y, Deng L, Li Q.   +7 more
europepmc   +1 more source