Results 161 to 170 of about 3,992,788 (314)

Improved stage-specific survival in screen-detected breast cancer in Denmark: a cohort study. [PDF]

J Natl Cancer Inst
Tickle A, Offman J, North B, Jørgensen SF, Njor S, Sasieni P.   +5 more
europepmc   +1 more source

Survival Methods [PDF]

Circulation, 2007
Sowmya R, Rao, David A, Schoenfeld
openaire   +2 more sources

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Time to Bystander Cardiopulmonary Resuscitation and Survival Outcomes in Pediatric Out-of-Hospital Cardiac Arrests in the United States. [PDF]

Circ Popul Health Outcomes
Abdel Jawad M, Abumuhfouz M, Spertus JA, Kennedy KF, Chan PS.   +4 more
europepmc   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Survivorship and Functional Outcomes after Surgery for Metastatic Spinal Disease Including Cord Compression: Single-Surgeon Cohort Series from UK Tertiary Center. [PDF]

J Orthop Case Rep
Marya A, Haruna M, Rishi A, de Matas M.
europepmc   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Nonparametric priors for vectors of survival functions [PDF]

The paper proposes a new nonparametric prior for two-dimensional vectors of survival functions (S1,S2). The definition we introduce is based on the notion of Lévy copula and it will be used to model, in a nonparametric Bayesian framework, two-sample ...
Antonio Lijoi, Ilenia Epifani
core  

Mechanical and manual cardiopulmonary resuscitation in traumatic cardiac arrest: a retrospective observational study. [PDF]

Eur J Trauma Emerg Surg
El-Menyar A, Ahmed K, Howland IR, Mollazehi M, Mekkodathil A, Rizoli S, Cameron P, de Oliveira Manoel AL, Al-Thani H.   +8 more
europepmc   +1 more source

Survival-related biases survive well [PDF]

International Journal of Epidemiology, 2006
openaire   +2 more sources