Results 181 to 190 of about 6,664,577 (297)

Surgical approach, relapse risk and overall survival in borderline ovarian tumors: age-stratified analysis based on real-world data. [PDF]

Front Oncol
Liuba K, Maciuszko N, Alson S, Asp M.
europepmc   +1 more source

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

Molecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor, Julio Celis, Ulrik Ringborg   +2 more
wiley   +1 more source

Patient pathways, presentation time, time to diagnosis, and early survival outcomes in pediatric acute lymphoblastic leukemia at Muhimbili National Hospital, Dar es Salaam, Tanzania. [PDF]

Front Pediatr
Philbert R, Mwamtemi H, Okade T, Mutyaba H, Ndyetabula L, Shimba E, Nakiddu NJ, Elisha E, Safari WC, Chiwanga F, Chirande L.   +10 more
europepmc   +1 more source

Insights into a long life without cancer: The case of the bowhead whale

Molecular Oncology, EarlyView.
Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley   +1 more source

Important Marine Mammal Areas celebrated—yet some are now in danger

Oryx
Erich Hoyt, Gill Braulik, Caterina Lanfredi, Gianna Minton, Simone Panigada, Elena Politi, Margherita Zanardelli, Giuseppe Notarbartolo di Sciara   +7 more
doaj   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

IUCN Species Survival Commission Amphibian Specialist Group launches Eastern Asian Salamander Task Force

Oryx
Amaël Borzée, Sally Wren, Vishal Kumar Prasad, Steven J. R. Allain, Janice Chanson, Kelsey Neam, Izabela Barata, Francis Asamoah, Jigme Wangyal, Maria Jose Chang, Dasi Ong   +10 more
doaj   +1 more source

Checkpoint blockade and the stem‐like T cell trade‐off

Molecular Oncology, EarlyView.
Stem‐like T cells are key to the success of programmed cell death protein 1 (PD1) blockade, as they sustain long‐term anti‐tumor response by continuously generating effector CD8+ T cells. However, how these cells are maintained in cancer is not fully understood. Hor et al.
Julie M. Mazet, Johanna A. Joyce
wiley   +1 more source

Influences of pupal presence and worker number on the survival and development of pharaoh ant (<i>Monomorium pharaonis</i>) brood under laboratory conditions. [PDF]

Anim Cells Syst (Seoul)
Baek HJ, Kim B.
europepmc   +1 more source

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source