Results 211 to 220 of about 4,475,446 (306)

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Current Trends in Therapeutic Outcomes Among Patients With Metastatic Renal Cell Carcinoma of the Spine: A Systematic Review and Meta-Analysis. [PDF]

Global Spine J
Ndika TC, Woo J, Lee BT, Johnson E, Oguguo E, Rivera N, Ray EJ, Bello A, Tiako JD, Mohamed L, Larry Lo SF, Sciubba DM, De la Garza Ramos R, O'Toole JE, Chongsathidkiet P, Dalton T, Crowell KA, Von Isenburg M, Mullikin T, Erickson M, Goodwin CR.   +20 more
europepmc   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Creation of the IUCN Species Survival Commission Gekkota Lizard Specialist Group

Oryx
Liliana Saboyá-Acosta, Thomas Ziegler, Andrea Echeverry-Alcendra, Jon Paul Rodríguez, Edgard Yerena   +4 more
doaj   +1 more source

Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for colorectal peritoneal metastases: a single-institution experience. [PDF]

Radiol Oncol
Pilko G, Petric R.
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Learning curve analysis for competency assessment in fetoscopic laser photocoagulation for twin-twin transfusion syndrome: A model for middle-resource settings. [PDF]

Pregnancy (Hoboken)
Marsoosi V, Eslamian L, Mohammadi S, Mohamadpour L, Abiad M, Javinani A, Shojaeian F, Rasekhi A, Shamshirsaz AA.   +8 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Restricted access zone declared in Greece to protect monk seals (perhaps)

Oryx
Giuseppe Notarbartolo di Sciara, Joan Gonzalvo   +1 more
doaj   +1 more source

Automated three-dimensional radiomic body composition analysis enhances survival prediction in resectable non‑small cell lung cancer. [PDF]

Eur Radiol Exp
Huang Y, Li C, Yang F, Chen X, Chen X, Huang Y, Zhang Z, Yang L, Jiang Y, Cun H, Mou Z, Yang W, Liu Z, He B.   +13 more
europepmc   +1 more source