Results 221 to 230 of about 9,160,314 (400)

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

Molecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti, Giovanni Germano, Pietro Paolo Vitiello, Alberto Bardelli   +3 more
wiley   +1 more source

BMI and PNI as predictors of treatment completion and survival in locally advanced HNSCC receiving sequential chemoradiotherapy. [PDF]

BMC Cancer
Zeynelgil E, Kavak EE, Dilli İ, İsak ÖA, Yazılıtaş D, İmamoğlu Gİ, Bayır Ö.   +6 more
europepmc   +1 more source

α1ACT Is Essential for Survival and Early Cerebellar Programming in a Critical Neonatal Window [PDF]

, 2019
Xiaofei Du, Cenfu Wei, Daniel Parviz Hejazi Pastor, Eshaan Rao, Yan Li, Giorgio Grasselli, Jack D. Godfrey, Ann C. Palmenberg, Jorge Andrade, Christian Hansel, Christopher M. Gómez   +10 more
openalex   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Introducing the Seaweed Specialist Group of the IUCN Species Survival Commission

Oryx
Nur Arafeh-Dalmau, Erlania, Emma Cebrian, Loyiso V. Dunga, Paulo Horta, Cayne Layton, Erasmo C. Macaya, Luisa Mangialajo, Pippa J. Moore, Alejandra Mora-Soto, Maggie M. Reddy, Albertus J. Smit, Pike Spector, Van Tu Nguyen, Jana Verdura, Jacqueline B. Pocklington   +15 more
doaj   +1 more source

Monoblock or modular? Impact of stem design and conicity angle on long-term implant survival in revision total hip arthroplasty: a 20-year follow-up registry study on 3647 implants. [PDF]

Eur J Orthop Surg Traumatol
Brunello M, Di Martino A, Morandi M, D'Agostino C, Di Censo C, Bordini B, Faldini C.   +6 more
europepmc   +1 more source

Methods for the analysis of quality-of-life and survival data in health technology assessment.

, 1999
Billingham, Abrams, Jones
openalex   +2 more sources

Resveratrol improves health and survival of mice on a high-calorie diet

Nature, 2006
J. Baur, K. Pearson, Nathan L. Price, H. Jamieson, C. Lerin, Avash Kalra, V. Prabhu, Joanne S. Allard, G. López-Lluch, Kaitlyn N. Lewis, P. Pistell, Suresh Poosala, K. Becker, O. Boss, Dana M. Gwinn, Mingyi Wang, S. Ramaswamy, K. Fishbein, R. Spencer, E. Lakatta, D. L. Couteur, R. Shaw, P. Navas, P. Puigserver, D. Ingram, R. Cabo, D. Sinclair   +26 more
semanticscholar   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

First study on the survival and dispersal of captive-reared narrow-headed softshell turtles along the Yamuna River, India

Oryx
Arunima Singh, Shailendra Singh, Adarsh Kumar, Pawan Shantiprakash Pareek, Sreeparna Dutta   +4 more
doaj   +1 more source