Results 111 to 120 of about 28,926,907 (345)

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

open access: yesMolecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh   +8 more
wiley   +1 more source

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

open access: yesMolecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song   +11 more
wiley   +1 more source

Adaptive Differential Privacy Cox-MLP Model Based on Federated Learning

open access: yesMathematics
In the data-driven healthcare sector, balancing privacy protection and model performance is critical. This paper enhances accuracy and reliability in survival analysis by integrating differential privacy, deep learning, and the Cox proportional hazards ...
Jie Niu   +6 more
doaj   +1 more source

Survival analysis of patients in the waiting list for kidney transplantation in terms of competing risks

open access: yesВестник трансплантологии и искусственных органов, 2019
Aim: to analyze the survival of patients on the waiting list for kidney transplantation and the results of transplantation depending on the duration of waiting.Materials and methods. We performed a retrospective observational analysis that included 1,197
A. V. Vatazin   +2 more
doaj   +1 more source

Survival analysis of the optical brightness of GRB host galaxies [PDF]

open access: yes, 2015
We studied the unbiased optical brightness distribution which was calculated from the survival analysis of host galaxies and its relationship with the Swift GRB data of the host galaxies observed by the Keck telescopes.
Bagoly, Z.   +3 more
core   +1 more source

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias   +12 more
wiley   +1 more source

Systemic meningococcal disease in children: survival analysis, Arkhangelsk region, Northwest Russia, 1991–2011

open access: yesЖурнал инфектологии, 2014
Systemic meningococcal infection requires prompt and adequate medical care. It is considered as unpredictable disease due to extreme severity of a patient’s condition and high risk for fatal outcome.
O. V. Samodova   +4 more
doaj   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner   +6 more
wiley   +1 more source

Performance of Indian Batsmen in the 2023 World Cup Squad - A Survival Analysis Approach

open access: yesStatistica
The game of cricket is enjoyed by millions of fans across the Globe. India is perusing the game like  anything. Though, at present, many local tournaments like IPL were conducted in India, the ability of the batsmen and their patterns of scoring runswere
Munusamy Ramakrishnan   +2 more
doaj   +1 more source

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