Results 111 to 120 of about 4,736,557 (326)

Computational Methods in Survival Analysis [PDF]

Survival analysis is widely used in the fields of medical science, pharmaceutics, reliability and financial engineering, and many others to analyze positive random phenomena defined by event occurrences of particular interest.
Kamakura, Toshinari
core  

Integrative analysis of circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients: a comprehensive approach

Molecular Oncology, EarlyView.
This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou, Argyro Roumeliotou, Evangelia Pantazaka, Athanasios‐Nasir Shaukat, Athina Christopoulou, Angelos Koutras, Foteinos‐Ioannis Dimitrakopoulos, Vassilis Georgoulias, Anastasia Xagara, Evangelia Chantzara, Fillipos Koinis, Athanasios Kotsakis, Constantinos Stathopoulos, Galatea Kallergi   +13 more
wiley   +1 more source

Survival analysis of DNA mutation motifs with penalized proportional hazards

, 2018
Antibodies, an essential part of our immune system, develop through an intricate process to bind a wide array of pathogens. This process involves randomly mutating DNA sequences encoding these antibodies to find variants with improved binding, though ...
Feng, Jean, Matsen IV, Frederick A., Minin, Vladimir N., Shaw, David A., Simon, Noah   +4 more
core   +2 more sources

The accumulation of myeloid‐derived suppressor cells participates in abdominal infection‐induced tumor progression through the PD‐L1/PD‐1 axis

Molecular Oncology, EarlyView.
This study explores how sepsis affects GC progression by creating an immunosuppressive environment. Our findings reveal that sepsis promotes immune dysregulation, enhancing tumor growth and metastasis. Targeting the PD‐1/PD‐L1 pathway with monoclonal antibodies shows potential for restoring immune function and improving outcomes in cancer patients ...
Yiding Wang, Ting Guo, Xiaofang Xing, Xijuan Liu, Xuejun Gan, Yingai Li, Yan Liu, Fei Shan, Zhouqiao Wu, Jiafu Ji, Ziyu Li   +10 more
wiley   +1 more source

The PTTG1/VASP axis promotes oral squamous cell carcinoma metastasis by modulating focal adhesion and actin filaments

Molecular Oncology, EarlyView.
VASP was found to be overexpressed in metastatic oral squamous cell carcinoma (OSCC) tissues. Notably, PTTG1‐ and VASP‐deficient OSCC cells demonstrated suppressed metastatic properties by disrupting the interaction between the cytoskeleton and focal adhesion (FAs) in the filopodia region.
Suyeon Park, Sang Shin Lee, Shihyun Kim, Yeonjun Lee, Gyeonwon Park, Jung Oh Kim, Jongho Choi   +6 more
wiley   +1 more source

Multivariate Frailty Modeling in Joint Analyzing of Recurrent Events with Terminal Event and its Application in Medical Data

مجله اپیدمیولوژی ایران, 2019
Background and Objectives: In many medical situations, people can experience recurrent events with a terminal event. If the terminal event is considered a censor in this type of data, the assumption of independence in the analysis of survival data may be
F Osmani, E Hajizadeh, AA Rasekhi, ME Akbari   +3 more
doaj  

Comprehensive Analysis of PD-1 Gene Expression, Immune Characteristics and Prognostic Significance in 1396 Glioma Patients

Cancer Management and Research, 2020
Chaojun Liu,1,* Zhen Zhang,1,* Yu Ping,1 Guohui Qin,1– 3 Kai Zhang,1 Nomathamsanqa Resegofetse Maimela,1 Lan Huang,1 Shengli Yang,1 Yi Zhang1– 3 1Biotherapy Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan ...
Liu C, Zhang Z, Ping Y, Qin G, Zhang K, Maimela NR, Huang L, Yang S, Zhang Y   +8 more
doaj  

Clustering Survival Data using a Mixture of Non-parametric Experts [PDF]

arXiv
Survival analysis aims to predict the timing of future events across various fields, from medical outcomes to customer churn. However, the integration of clustering into survival analysis, particularly for precision medicine, remains underexplored. This study introduces SurvMixClust, a novel algorithm for survival analysis that integrates clustering ...
arxiv  

Survival analysis [PDF]

, 2005
Survival analysis pertains to a statistical approach designed to take into account the amount of time an experimental unit contributes to a study. A Mayo Clinic study of 418 Primary Biliary Cirrhosis patients during a ten year period was used. The Kaplan-
Wardak, Mohammad Alif
core   +1 more source

PROBIT ANALYSIS APPLIED TO SALMONELLA PULLORUM SURVIVAL DATA [PDF]

, 1956
William Dowell Baten, H. J. Stafseth
openalex   +1 more source