Results 191 to 200 of about 4,736,557 (326)

A SIMULATION STUDY OF CROSS‐VALIDATION FOR SELECTING AN OPTIMAL CUTPOINT IN UNIVARIATE SURVIVAL ANALYSIS [PDF]

, 1996
DAVID FARAGGI, RICHARD SIMON
openalex   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Treatment planning with a 2.5 MV photon beam for radiation therapy

Journal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract Purpose The shallow depth of maximum dose and higher dose fall‐off gradient of a 2.5 MV beam along the central axis that is available for imaging on linear accelerators is investigated for treatment of shallow tumors and sparing the organs at risk (OARs) beyond it.
Navid Khaledi, Chris Hayes, Louise Belshaw, Mark Grattan, Rao Khan, James L. Gräfe   +5 more
wiley   +1 more source

Survival analysis using machine learning in transplantation: a practical introduction. [PDF]

BMC Med Inform Decis Mak
Garcia-Lopez A, Jiménez-Gómez M, Gomez-Montero A, Gonzalez-Sierra JC, Cabas S, Giron-Luque F.   +5 more
europepmc   +1 more source

Statistical analysis on the postoperative survivals of cancer patients in treatment of SSM (an extract from human tubercle bacilli, so called Maruyama vaccine).

, 1985
Kazumi Iida, Toshiyuki Hirai, Hiroko Iwaki, Keishiro Fujita, Chisato Maruyama, Akihiko Miyake, Shuichi Shinmura   +6 more
openalex   +2 more sources

How heritable is individual susceptibility to death? The results of an analysis of survival data on Danish, Swedish and Finnish twins [PDF]

, 1998
Ivan A. Iachine, Niels V. Holm, Jennifer R. Harris, Alexander Z. Begun, Maria Iachina, Markku Laitinen, Jaakko Kaprio, Anatoli I. Yashin   +7 more
openalex   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Clinical characteristics and survival analysis of cancer of unknown primary. [PDF]

Oncol Lett
Ma M, Guo B, Duan Q, Jiao P, Bi J, Wei S, Wang J, Zhang F, Xu Y, Zhang P, He M, Jin J.   +11 more
europepmc   +1 more source

Mixture models for cancer survival analysis: application to population‐based data with covariates [PDF]

, 1999
R. De Angelis, R. Capocaccia, T. Hakulinen, B. Soderman, A. Verdecchia   +4 more
openalex   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source