Results 241 to 250 of about 4,850,533 (302)

Bayesian generalized method of moments applied to pseudo-observations in survival analysis. [PDF]

open access: yesLifetime Data Anal
Orsini L   +5 more
europepmc   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Fluorescence-Based Soil Survival Analysis of the Xenobiotic- and Metal-Detoxifying <i>Streptomyces</i> sp. MC1. [PDF]

open access: yesInt J Mol Sci
Aparicio JD   +5 more
europepmc   +1 more source

Ten year survival after repeat local treatment for colorectal liver metastases: a multicenter analysis [PDF]

open access: bronze
Loubna Outmani   +6 more
openalex   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

Survival Rate of Breast Cancer in Iran: A Meta-Analysis

open access: green, 2016
Ghasem Abedi   +5 more
openalex   +1 more source

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