Results 251 to 260 of about 28,159,239 (344)

Pericytes change function depending on glioblastoma vicinity: emphasis on immune regulation

Molecular Oncology, EarlyView.
Pericytes alter their transcriptome depending on their proximity to the tumor core. In the tumor core, pericytes display a more active state with higher communication strength but with lower immune activation potential and a shift toward extracellular matrix production.
Carolina Buizza, Robert Carlsson, Coralie Gamper, Gayatri Chitale, Johan Bengzon, Gesine Paul   +5 more
wiley   +1 more source

Long-Term Survival Analysis of Neoadjuvant Chemoradiotherapy Versus Adjuvant Chemoradiotherapy for Locally Advanced Low Rectal Cancer. [PDF]

Cancer Med
Chen S, Wu R, Wan J, Xu Y, Wang Y, Zhang Z, Huang L, Liu Y, Lin Y, He L, Deng Y, Xia F, Xu Y, Zhang Z, Zheng H.   +14 more
europepmc   +1 more source

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source

Conditional survival analysis and real-time prognosis prediction for prostate cancer patients. [PDF]

Sci Rep
Xu L, Mao X, Ding Y, Zhou Z, Chen Y, Wang M, Li G, Lu Z.   +7 more
europepmc   +1 more source

Modeling the Effect of a Disease on Culling: An Illustration of the Use of Time-Dependent Covariates for Survival Analysis

, 1997
Y.T. Gröhn, Vincent Ducrocq, J.A. Hertl
openalex   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Improving the Estimation of Prediction Increment Measures in Logistic and Survival Analysis. [PDF]

Cancers (Basel)
Enserro DM, Miller A.
europepmc   +1 more source

Single‐cell transcriptomics redefines focal neuroendocrine differentiation as a distinct prostate cancer pathology

Molecular Oncology, EarlyView.
Single‐cell transcriptomics of prostate cancer patient‐derived xenografts reveals distinct features of neuroendocrine (NE) subtypes. Tumours with focal NE differentiation (NED) share transcriptional programmes with adenocarcinoma, differing from large and small cell neuroendocrine prostate cancer (NEPC). Our work defines the molecular landscape of NEPC,
Rosalia Quezada Urban, Shivakumar Keerthikumar, Ashlee Clark, Hong Wang, Belinda Phipson, Andrew Bakshi, Andrew Ryan, Heather Thorne, Renea A. Taylor, Mitchell G. Lawrence, Gail P. Risbridger, Roxanne Toivanen, David L. Goode   +12 more
wiley   +1 more source

Clinical diagnosis, treatment, and survival analysis of 61 cases of salivary duct carcinoma: a retrospective study. [PDF]

PeerJ
Dong S, Li M, Zhang Z, Feng B, Ding W, Chang J, Liu F.   +6 more
europepmc   +1 more source

Evaluation of the Effectiveness of Lung Cancer Screening in Sukumo City: An Attempt to Eliminate the Length Bias from Survival Analysis with Consideration of Screening History.

, 1995
Tetsuo Tamura, Hidetoshi Yamashita, Daihachi Tsutsui, Kenichi Machida, Hirohumi Tokuoka, Tadashi Takashima, Takaichiro Suzuki, Yoshiaki Moritani   +7 more
openalex   +2 more sources