Results 291 to 300 of about 28,926,907 (345)

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Population-Based Survival Analysis of Solitary Plasmacytoma of Spine in the United States From 2000 to 2020. [PDF]

Cancer Rep (Hoboken)
Agner KE, Comisford LG, Kotler AG, Wells JA, Larkins MC.   +4 more
europepmc   +1 more source

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

FEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

Clinical Characteristics and Survival Analysis of Patients with Supraclavicular Fossa Lymphadenopathy. [PDF]

Diagnostics (Basel)
Kao YJ, Hsu WL, Chen YC, Lo WC, Cheng PC, Liao LJ.   +5 more
europepmc   +1 more source

Ordinal Multi-modal Feature Selection for Survival Analysis of Early-Stage Renal Cancer

, 2018
Wei Shao, Jun Cheng, Liang Sun, Zhi Han, Qianjin Feng, Daoqiang Zhang, Kun Huang   +6 more
openalex   +1 more source

Protein Tyrosine Phosphatase 4A1 (PTP4A1) Regulates Early Events in Colorectal Cancer Intraperitoneal Dissemination in the Aged Male Host

Aging and Cancer, EarlyView.
Colorectal cancer (CRC) mortality is highest in aged males. Pre‐clinical data comparing CRC i.p. metastasis in cohorts of young and aged, male and female mice support these finding. Bottom‐up proteomics of peritoneal mesothelial cells identified PTP4A1 as highly expressed in aged males and a role for PTP4A1 in heterotypic cell:cell adhesion was ...
Zhikun Wang, Yueying Liu, Jing Yang, Tyvette S. Hilliard, Reihaneh Safavi‐Sohi, Daniel D. Hu, Elizabeth I. Harper, Gena Dominique, Wanrui Wang, Jeffrey Johnson, Marwa Asem, William Milosevich, Julia Florek Carlson, Yunpeng Bai, Jinmin Miao, Zhong‐Yin Zhang, Matthew M. Champion, M. Sharon Stack   +17 more
wiley   +1 more source

Classification of Clinical Outcomes in Hospitalized Asian Elephants Using Machine Learning and Survival Analysis: A Retrospective Study (2019-2024). [PDF]

Vet Sci
Kosaruk W, Punyapornwithaya V, Ueangpaiboon P, Angkawanish T.   +3 more
europepmc   +1 more source

Trends and Disparities in Lung Cancer and Respiratory Failure Mortality in the United States: A 24‐Year Retrospective Study

Aging and Cancer, EarlyView.
Mortality from lung cancer and respiratory failure in US adults declined until 2010 but increased thereafter, with notable disparities by sex, race, region, and urbanicity. This 24‐year analysis highlights rising post‐2010 mortality in women, non‐Hispanic Whites, and urban areas, underscoring the need for targeted public health interventions.
Sardar M. I. Khan, Muneeb Khawar, Abdul Qadeer, Aqsa Komel, Azka Aisha, Arshia Batool, Ayesha Fatima, Javed Iqbal, Asraf Hussain, Anisha Manzoor, Muhammad Waqas   +10 more
wiley   +1 more source

Dynamic survival analysis via a landmarking-gradient boosting approach and its application to kidney transplant data. [PDF]

BMC Med Inform Decis Mak
Shabani N, Yaseri M, Alimi R, Nazemian F, Zeraati H.   +4 more
europepmc   +1 more source

Using interpretable survival analysis to assess hospital length of stay. [PDF]

BMC Health Serv Res
Li Y, Hall T, Razak F, Verma A, Chignell M, Wang L.   +5 more
europepmc   +1 more source