Prognostic Factors and Survival Data of Stage I Lung Cancer: A Single-Center Experience. [PDF]
J Clin Pract ResArici MO +6 more
europepmc +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Reconstructing patient level survival data from published Kaplan-Meier curves. [PDF]
Contemp Clin Trials CommunKim J, Chalise P, He J.
europepmc +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
A Two-Step Variable Selection Strategy for Multiply Imputed Survival Data Using Penalized Cox Models. [PDF]
Bioengineering (Basel)Yang Q, Luo B, Yu C, Halabi S.
europepmc +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
NMAsurv: An R Shiny application for network meta-analysis based on survival data. [PDF]
Res Synth MethodsShao T, Zhao M, Shi F, Rui M, Tang W.
europepmc +1 more source
Quantile forward regression for high-dimensional survival data. [PDF]
Lifetime Data Anal, 2023 Lee ER, Park S, Lee SK, Hong HG.
europepmc +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Germ cell tumours of the testis: 10-year survival data from a tertiary care centre in India. [PDF]
EcancermedicalscienceGupta N +4 more
europepmc +1 more source