Results 171 to 180 of about 2,431,681 (314)
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Tree-structured analysis of survival data
, 2010 The purpose of this paper is to classify UIS data in order to identify their risk, reduce drug abuse, and to prevent high-risk in HIV behavior. A method for fitting proportional hazards models to censored survival data is described.
Ismail, Moshirah. +2 more
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A unified framework for complex survival data: accounting for clustering, cure fractions, and competing risks. [PDF]
BMC Med Res MethodolWang Y, Li J, Zhou Q, Wang W.
europepmc +1 more source
Molecular Oncology, EarlyView.Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
wiley +1 more source
Nonparametric Bayesian Inference For Survival Data
, 2007 This article introduces a new Bayesian approach to the analysis of right-censored survival data. The hazard rate of interest is modeled as a product of conditionally independent stochastic processes, corresponding to (1) a baseline hazard function, and ...
Ian W. MCKEAGUE, Mourad Tighiouart
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CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
MiR‐513a promotes human erythroid differentiation by modulating c‐Jun
FEBS Open Bio, EarlyView.During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim +11 more
wiley +1 more source
A-calibration: assessment of prediction models for survival data under censoring. [PDF]
BMC Med Res MethodolSimonsen MR, Waagepetersen RP.
europepmc +1 more source
FEBS Open Bio, EarlyView.Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao +3 more
wiley +1 more source
Gene selection for survival data under dependent censoring, a copula-based approach
, 2014 [[sponsorship]]統計科學研究所[[note]]出版中(submitted);沒有審查制度 ...
Emura, T.;Chen, Y. -H.
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