Results 181 to 190 of about 4,636,420 (247)

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Latent Class Proportional Hazards Regression with Heterogeneous Survival Data. [PDF]

Stat Interface
Fei T, Hanfelt JJ, Peng L.
europepmc   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Recent advances in systemic therapy for advanced biliary tract cancer: A systematic review and meta-analysis using reconstructed RCT survival data. [PDF]

JHEP Rep
Li Z, Aliseda D, Jones O, Rajendran L, Magyar C, Grant R, O'Kane GM, Saborowski A, Sapisochin G, Vogel A.   +9 more
europepmc   +1 more source

Preoperative CT and survival data for patients undergoing resection of colorectal liver metastases. [PDF]

Sci Data
Simpson AL, Peoples J, Creasy JM, Fichtinger G, Gangai N, Keshavamurthy KN, Lasso A, Shia J, D'Angelica MI, Do RKG.   +9 more
europepmc   +1 more source

Associations between modifiable risk factors and cognitive function in middle-aged and older Chinese adults: joint modelling of longitudinal and survival data. [PDF]

Front Public Health
Ran Q, Yang F, Su Q, Li P, Hu Y.
europepmc   +1 more source

Ambulatory Routine Care in Oncology in Germany: Real-World Survival Data.

Oncol Res Treat
Marschner N, Knauf W.
europepmc   +1 more source