Results 231 to 240 of about 17,500,545 (334)

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Durvalumab-Tremelimumab in Advanced Hepatocellular Carcinoma: Real-World Data From the LOR-HCC (Lombardy Real-World HCC Group). [PDF]

Liver Int
Casadei-Gardini A, Canova L, Tosi F, Camera S, Bocchero E, Pozzoni P, Torchio M, Corallo S, Costantino D, Stagno A, Grizzi G, Gengarle R, Tomasello G, Ansarin N, Bruccoleri M, Bencardino K, Persano M, Pino M, Riva A, Vavassori S, Argiento L, Mazzarelli C, De Giorgio M, Caremoli ER, Rimini M, Pressiani T, Rimassa L, Iavarone M.   +27 more
europepmc   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Topology-Based Biomarkers Accurately Predict Breast Cancer Outcome and Survival. [PDF]

Cancer Res
Singhal S, Li C, Aukerman A, Carrière M, Miller ML, Hibshoosh H, McDonald JA, Winfield JR, Aung STH, Martinez-Delgado G, Frankenstein Z, Lee YH, Rabadan R, Saltz J, Chen C, Gardner K.   +15 more
europepmc   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Hypothermic Machine Perfusion Allows Safe Delay in Kidney Transplantation After Cold Storage. [PDF]

J Clin Med
Macech M, Grochowiecki TR, Wojtaszek E, Nazarewski S, Glogowski T, Mondryk A, Proczka MS, Michalska MN, Malyszko J, Galazka Z.   +9 more
europepmc   +1 more source

Empirical Bayes Estimation of a Distribution (Survival) Function from Right Censored Observations

, 1978
V. Susarla, J. Ryzin
semanticscholar   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Comparative Analysis of Kidney and Simultaneous Pancreas-Kidney Transplantation: Long-Term Outcomes in Type 1 Diabetic Patients with End-Stage Kidney Disease. [PDF]

J Clin Med
Ziaja J, Widera M, Kolonko A, Owczarek AJ, Kamińska D, Świder R, Góral A, Sekta S, Król R, Czerwiński J, Durlik M, Więcek A.   +11 more
europepmc   +1 more source