Results 251 to 260 of about 1,812,936 (307)

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

FEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura, Kengo Furuichi, Hiromitsu Akamatsu, Naoki Yamamoto, Sako Keisuke, Akihiko Koshino, Taichiro Minami, Megumi Oshima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kenta Takahashi, Minako Yamamura, Shin‐ichi Horike, Takiko Daikoku, Kenichi Harada, Yohei Shinmyo, Hiroshi Kawasaki, Takashi Wada, Yasunori Iwata   +19 more
wiley   +1 more source

DNA damage complexity as a predictor of cell survival: a microscopic Monte Carlo-based modeling framework for photon, proton and carbon ion irradiation. [PDF]

Phys Med Biol
Qi M, Lai Y, Guan F, Xing M, Bronk L, Mohan R, Li H, Chi Y, Jia X.   +8 more
europepmc   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Cardiopulmonary resuscitation in donation after brain death donors aged ≥65 years: impact on outcomes after kidney transplantation - a multi-center study. [PDF]

Transpl Int
Süsal CC, Bachmann Q, Kälble F, Mahler CF, Ott M, Heymer J, Braunisch M, Assfalg V, Dippon J, Heemann U, Renders L, Schwenger V, Echterdiek F.   +12 more
europepmc   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

"Mycophenolate-Based Immunosuppression After Calcineurin-Inhibitor Withdrawal in Liver Transplant Recipients is Safe and Results in Long-Term Improvement in Renal Function". [PDF]

Clin Transplant
Lim N, Vock D, Jackson S, Lake J.
europepmc   +1 more source

Patient outcomes following extracorporeal membrane oxygenation support for severe COVID-19 acute respiratory distress syndrome. [PDF]

Proc (Bayl Univ Med Cent)
Eisenga JB, McCullough KA, Moubarak G, Shih E, Banwait J, Vaishnav R, Sheasby J, Myers D, Awad O, DiMaio JM, George TJ.   +10 more
europepmc   +1 more source

Long-term renal function and complication profiles after ABO-incompatible <i>vs</i> compatible living-donor kidney transplantation: A single-center experience. [PDF]

World J Transplant
Braga BG, Cunha A, Almeida M, Sousa S, Trigo AF, Inácio A, Dias B, Silvano J, Ribeiro C, Pedroso S, Sampaio M, Bini-Antunes M, Martins S.   +12 more
europepmc   +1 more source

Correlation of Controlling Nutritional Status Score and Systemic Immune-Inflammation Index With Frailty and Prognosis in Chronic Heart Failure Patients With Atrial Fibrillation. [PDF]

Cardiol Res Pract
Wang J, Xing JW, Bo GG.
europepmc   +1 more source

Defining Long-term Success after Anterior Augmentation Urethroplasty: 10-yr Patient-reported and Objective Outcomes According to the Novel Stricture-fecta Criteria. [PDF]

Eur Urol Open Sci
Klemm J, Schulz RJ, Roessler N, Wagner MC, Dahlem R, Fisch M, Vetterlein MW.   +6 more
europepmc   +1 more source