Results 261 to 270 of about 174,614,231 (302)

Human Dental Pulp Stem Cell Secretome Restores Ischemic Stroke–Impaired Motor and Cognitive Functions by Reprogramming Redox and Inflammatory Signaling

Advanced Science, EarlyView.
Human dental pulp stem cell secretome emerges as a cell‐free therapeutic strategy for ischemic stroke by reprogramming redox and inflammatory signaling. hDPSC secretome‐derived antioxidant and immunomodulatory factors suppress the TLR4–NOX–ROS–NF‐κB axis, reduce microglial inflammatory responses and apoptosis, and promote neurogenesis, angiogenesis ...
Kyung‐Joo Seong, Sehoon Park, Sun‐Woong Bae, Daseul Kim, Jin Ho Lee, Won‐Seok Choi, Zee‐Yong Park, Ji‐Yeon Jung, Won‐Jae Kim   +8 more
wiley   +1 more source

Neurotropic alphavirus infection induces PARP-1 hyperactivation-mediated energy collapse in motor neurons. [PDF]

J Virol
Williams RE, Pieterse L, Patel SS, McLaren MW, Elrick MJ, Griffin DE.   +5 more
europepmc   +1 more source

A Panel of Circulating Exosomal sncRNAs Associated With Lung Cancer Risk up to 10 Years in Advance

Advanced Science, EarlyView.
Lung cancer is often diagnosed too late, and current screening overlooks many people at risk. In a long‐term study of smokers, a panel of small non‐coding RNAs carried in blood exosomes signals elevated lung cancer risk up to ten years before diagnosis, pointing toward a blood‐based tool for earlier risk detection.
Zhuokun Feng, Masaki Nasu, Ayman Abdul‐Ghani, Yu Chen, Shaoqiu Chen, Isam Mohd Ibrahim, Hanqiu Zhang, Lauren Higa, Zitong Gao, Hua Yang, Raphael Bueno, Loïc Le Marchand, Youping Deng   +12 more
wiley   +1 more source

Spinal muscular atrophy in the disease-modifying therapy era: successes, limitations and future directions. [PDF]

Front Mol Med
Sexton MM, Crow EW, Peng CA.
europepmc   +1 more source

Dynamic integration of skeletal muscle signals via extracellular vesicles in motor neuron diseases. [PDF]

Acta Neuropathol Commun
Riggio F, Fenili G, Caporossi D, Paronetto MP.   +3 more
europepmc   +1 more source

Direct neuronal reprogramming for neurological diseases: applications, translational Challenges, and future directions. [PDF]

Front Neurosci
Chen Y, Zheng Z, Zhao P, Zhu J, Sun H, Zhu H, Zeng Y, Shang B, Zhang A, Pan Y, Wang K.   +10 more
europepmc   +1 more source

Protein arginine methyltransferases coordinate mitochondrial stress adaptation and neuromuscular function. [PDF]

Exp Mol Med
Bae JH, You CL, Park J, Kang JS.
europepmc   +1 more source