Results 121 to 130 of about 4,464,251 (309)
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Frontiers in ImmunologyBackgroundFirst-line immunotherapy combined with chemotherapy for extensive-stage small-cell lung cancer (ES-SCLC) has been consistently recommended by clinical guidelines, but the improvement in overall survival remains limited.
Yalan Liu +6 more
doaj +1 more source
P60.04 TTF1 Expression in Advanced Lung Adenocarcinoma and Survival Outcome: An Observational Study
, 2021 P60.04 TTF1 Expression in Advanced Lung Adenocarcinoma and Survival Outcome: An Observational ...
R Webster (13014528) +3 more
core
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
CYP2B6 SNPs correlated with objective response and survival outcome (crude analysis).
, 2016 CYP2B6 SNPs correlated with objective response and survival outcome (crude analysis).
Reem M. Hesham (3157503) +4 more
core +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Characteristics of the study population according to hospital survival and neurological outcome.
, 2018 Characteristics of the study population according to hospital survival and neurological outcome.
Leda Nobile (3558893) +10 more
core +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
CROP DIVERSITY AS THE DERIVED OUTCOME OF FARMERS' 'SURVIVAL FIRST' MOTIVES IN ETHIOPIA: WHAT ROLE FOR ON-FARM CONSERVATION OF SORGHUM GENETIC RESOURCES? [PDF]
Crop genetic resources are the building blocks of sustainable agricultural development due to their relevance not only as inputs for variety development but also as indigenous crop insurance mechanisms through traditional variety portfolio management ...
Virchow, Detlef, Wale, Edilegnaw
core